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Now showing items 21-29 of 29
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R-Ras Glucosylation and transient RhoA activation determine the cytopathic effect produced by Toxin B variants from Toxin A-negative strains of clostridium difficile
(American Society for Biochemistry and Molecular Biology, 2003-03-07)Clostridium difficile induces antibiotic-associated diarrhea through the production of toxin A and toxin B; the former toxin has been assumed to be responsible for the symptoms of the disease. Several toxin A-negative ... -
Regulation of Brucella virulence by the two-component system BvrR/BvrS
(Elsevier B.V., 2002-12-20)The Brucella BvrR/BvrS two-component regulatory system is highly similar to the regulatory and sensory proteins of Sinorhizobium and Agrobacterium necessary for endosymbiosis and pathogenicity in plants, and very similar ... -
Serological diagnosis of brucella infections in odontocetes
(American Society for Microbiology, 2009-04-15)Brucella ceti causes disease in Odontoceti. The absence of control serum collections and the diversity of cetaceans have hampered the standardization of serological tests for the diagnosis of cetacean brucellosis. Without ... -
The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens
(PLOS ONE, 2009-06-16)Background: During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some a-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. ... -
The horse as a model for translational orthopedic research: examples of studies on the regeneration of cartilage and bone conducted in Costa Rica
(Universidad Nacional, Costa Rica, 2019)The paper provides results published or to be published of long-term in vivo equine studies to evaluate techniques of possible regenerative matrices of cartilage and bone, by means of cell-free implants or ... -
The two-component system BvrR BvrS essential for Brucella abortus virulence regulates the expression of outer membrane proteins with counterparts in members of the Rhizobiaceae
(Proceedings of the National Academy of Sciences, 2002-09-17)The Brucella BvrR/BvrS two-component regulatory system is homologous to the ChvI/ChvG systems of Sinorhizobium meliloti and Agrobacterium tumefaciens necessary for endosymbiosis and pathogenicity in plants. BvrR/BvrS ... -
The two-component system BvrR/BvrS regulates the expression of the Type IV secretion system VirB in Brucella abortus
(American Society for Microbiology, 2010-11)The pathogenesis of Brucella is related to the ability to multiply intracellularly, an event controlled by the two-component system BvrR/BvrS (TCS BvrRS) and the type IV secretion machinery VirB (T4SS VirB). We have ... -
The use of green fluorescent protein as a marker for Brucella vaccines
(Elsevier, 2010-11-04)La brucelosis es una importante enfermedad de los animales de producción y de la fauna silvestre y una zoonosis mundial. El uso de vacunas eficaces y las correspondientes pruebas de diagnóstico que permiten diferenciar los ... -
Tratamiento de sarcoide equino: reporte de cuatro casos clínicos
(Universidad Nacional, Costa Rica, 2015-05-08)El sarcoide equino es el tumor cutáneo más frecuente en caballos, con presentaciones y localizaciones variables en la piel. Este artículo tiene como objetivo describir la presentación, el abordaje y la evolución de cuatro ...