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Desarrollo y validación química y serológica de un ensayo inmunoenzimático ELISA para el diagnóstico de la brucelosis en odontocetos
(Universidad Nacional, Costa Rica, 2006)
Miembros del género Brucella, conocidos como “Brucella cetaceae” son patógenos de
marsopas, delfines y ballenas. La experiencia clínica y el conocimiento de la patobiología de
este microorganismo son limitados; sin ...
Estudios anátomo-histopatológicos e inmunohistoquímicos sobre las patologías de los cetáceos encallados en Costa Rica durante el período 2001-2007. Con énfasis especial en el diagnóstico de Brucella y Morbillivirus
(Universidad Nacional, Costa Rica, 2008)
Costa Rica cuenta con una extensión marítima diez veces mayor a su extensión terrestre. En
estas aguas habita el treinta y cinco por ciento de la biodiversidad mundial de cetáceos,
representada por aproximadamente 29 ...
Regulation of Brucella virulence by the two-component system BvrR/BvrS
(Elsevier B.V., 2002-12-20)
The Brucella BvrR/BvrS two-component regulatory system is highly similar to the regulatory and sensory proteins of Sinorhizobium and Agrobacterium necessary for endosymbiosis and pathogenicity in plants, and very similar ...
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum
(The Rockefeller University Press, 2003-01-18)
The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide zoonosis
that affects mammals, including humans. Essential to Brucella virulence is its ability to survive and
replicate inside host ...
Characterization of Brucella abortus lipopolysaccharide macrodomains as mega rafts
(Blackwell Science, 2005-09-28)
The lipopolysaccharides (LPS) of intracellular Proteobacteria such as Brucella, Chlamydia, Legionella and Rickettsia, have properties distinct from enterobacterial LPSs. These properties include deficient LPS induction of ...
Comparison of the antibody response in adult cattle against different epitopes of Brucella abortus lipopolysaccharide
(Blackwell, 2001)
The comparison of serological responses in a sample of adult, vaccinated and held-infected bovines with Brucella abortus is reported. Indirect enzyme immunoassav (EIA) titration curves and Western blotting tests for ...
Extensive Cell Envelope Modulation Is Associated with Virulence in Brucella abortus
(American Chemical Society, 2007-08-03)
Brucella virulence is linked to components of the cell envelope and tightly connected to the function of
the BvrR/BvrS sensory-regulatory system. To quantify the impact of BvrR/BvrS on cell envelope proteins,
we performed ...
MyD88, but not Toll-Like receptors 4 and 2, Is required for efficient clearance of Brucella abortus
(American Society for Microbiology, 2005-08)
It is not clear how the host initially recognizes and responds to infection by gram-negative pathogenic
Brucella spp. It was previously shown (D. S. Weiss, B. Raupach, K. Takeda, S. Akira, and A. Zychlinsky, J.
Immunol. ...
Brucella melitensis: a nasty bug with hidden credentials for virulence
(The National Academy of Sciences, 2002-01-08)
On September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal ...
Brucella intracellular life: from invasion to intracellular replication
(Elsevier, 2002)
Brucella organisms are pathogens that ultimate goal is to propagate in their preferred niche, the cell. Upon cell contact the bacteria is internalized via receptor molecules by activating small GTPases of the Rho subfamily ...