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A two-component regulatory system playing a critical role in plant pathogens and endosymbionts is present in Brucella abortus and controls cell invasion and virulence
(Blackwell Science, 1998-04-08)
Two mutants showing increased sensitivity to polycations and surfactants were obtained by transposon mutagenesis of virulent Brucella abortus 2308 Nal(r). These mutants showed no obvious in vitro growth defects and produced ...
An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes
(Elsevier, 1992)
The number and isoelectric points of phospholipase A2 isoenzymes were studied in the venoms of 12 Central American crotaline snakes of the genera Bothrops, Crotalus, Lachesis and Agkistrodon. The study was carried out by ...
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region
(Elsevier, 2005)
A short peptide derived from the C-terminal region of Bothrops asper myotoxin II, a Lys49 phospholipase A2 (PLA2), was previously found to reproduce the bactericidal activity of its parent molecule. In this study, a panel ...
Regulation of Brucella virulence by the two-component system BvrR/BvrS
(Elsevier B.V., 2002-12-20)
The Brucella BvrR/BvrS two-component regulatory system is highly similar to the regulatory and sensory proteins of Sinorhizobium and Agrobacterium necessary for endosymbiosis and pathogenicity in plants, and very similar ...
A new method for the detection of phospholipase A2 variants: Identification of isozymes in the venoms of newborn and adult Bothrops asper (terciopelo) snakes
(Elsevier B.V, 1988)
E. Moreno, A. Alape, M. Sánchez and J. M. Gutiérrez. A new method for the detection of phospholipase A2 variants: identification of isozymes in the venoms of newborn and adult Bothrops asper (terciopelo) snakes. Toxicon ...
A sensitive blotting system for detection of α-fetoprotein variants with monoclonal and polyclonal antibodies
(Elsevier, 1988-08-19)
Human α-fetoprotein (AFP) variants from cord sera were separated by isoelectric focusing in agarose gels under native conditions, transferred to nitrocellulose paper and detected with polyclonal and monoclonal antibodies ...
Bactericidal and Antiendotoxic Properties of Short Cationic Peptides Derived from a Snake Venom Lys49 Phospholipase A2
(American Society for Microbiology, 2005-04)
The activities of short synthetic, nonhemolytic peptides derived from the C-terminal region of myotoxin 11, a catalytically inactive phospholipase A(2) homologue present in the venom of the snake Bothrops asper, have been ...
Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom Synthetic Lys49 myotoxin II-(115−129)-peptide identifies its bactericidal region
(FEBS, 1998)
Mammalian group-II phospholipases A2 (PLA2) of inflammatory fluids display bactericidal properties, which are dependent on their enzymatic activity. This study shows that myotoxins II (Lys49) and III (Asp49), two group-II ...
Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes
(Pergamon Press, 1987-10-23)
E. Moreno and J. M. Gutiérrez. Body distribution of Bothrops asper (terciopelo) snake venom myotoxin and its relationship to pathological changes. Toxicon 26, 403 - 409, 1988. - The distribution of 125I-labelled Bothrops ...
Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum
(The Rockefeller University Press, 2003-01-18)
The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide zoonosis
that affects mammals, including humans. Essential to Brucella virulence is its ability to survive and
replicate inside host ...