Póster de Congreso

URI permanente para esta colecciónhttp://10.0.96.45:4000/handle/11056/20323

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Tubulo-papillary renal cell carcinoma in a captive ocelot (Leopardus pardalis)
(American College of Veterinary Pathologists, 2022-11-14) Romero-Vega, L. Mario; Hagnauer, Isabel; Alfaro-Alarcon, Alejandro
A 12 years old captive ocelot (Leopardus pardalis) was diagnosed with a 2.6x2.2x1.6 cms mass on the cranial pole of the right kidney. No other macroscopic changes were observed during necropsy. The mass was processed by standard Hematoxilin & Eosin staining. Periodic Acid-Schiff (PAS)staining was also performed. The tissue was analyzed for the following markers by immunohistochemistry: WT1, CK Ae1/A3, CK19, CK 7, Vimentin , Melan-1, and HMB45. Only vimentin had a positive stain. Under microscopic examination, the mass was surrounded by a fibrous pseudocapsule and compressed the adjacent normal renal. The tumoral cells are small cuboidal epithelial cells arranged in a single layer. The tissue cells have lightly eosinophilic cytoplasm, a rounded nucleus, and no mitoses. The epithelial cells grow in a papillary pattern which contains pseudo-rosettes in their lumen. Some of these pseudo-rosettes contain a PAS positive material, most likely Tamm-Horsfall protein. The stroma was also PASpositive. The number of pseudorosettes varies from one to several in each tubule. Based on this finding, the tumor was classified as a tubulo-papillary renal cell carcinoma. Although this neoplasia is well described in domestic cats, it is rarely reported in wild felids. To our best knowledge, this is the first renal carcinoma reported in the Pardalis genera, which includes 13 new world felids. Its occurrence in an Ocelot is valuable since neoplasias in this specie are rarely reported in Latin America.

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Examinando Póster de Congreso por Materia "ANIMAL PATOLOGY"