Artículos científicos

URI permanente para esta colecciónhttp://10.0.96.45:4000/handle/11056/14755

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Agricoh: A consortium of agricultural cohorts
(Multidisciplinary Digital Publishing Institute(MDPI), Switzerland., 2011-04-29) Leon, Maria; Beane Freeman, Laura; Douwes, Jeroen; Hoppin, Jane; Kromhout, Hans; Lebailly, Pierre; Christian Nordby, Karl; Schenker, Marc; Schüz, Joachim; Waring, Stephen; Alavanja, Michael; Annesi Maesano, Isabella; Baldi, Isabelle; Aqiel Dalvie, Mohamed; Ferro, Giles; Fervers, Beatris; Langseth, Hilde; London, Leslie; Lynch, Charles; McLaughlin, John; Merchant, James; Pahwa, Punam; Sigsgaard, Torben; Stayner, Leslie; Wesseling, Catharina; Keun-Young, Yoo; Zahm, Sheila; Straif, Kurt; Blair, Aaron
AGRICOH is a recently formed consortium of agricultural cohort studies involving 22 cohorts from nine countries in five continents: South Africa (1), Canada (3), Costa Rica (2), USA (6), Republic of Korea (1), New Zealand (2), Denmark (1), France (3) and Norway (3). The aim of AGRICOH, initiated by the US National Cancer Institute (NCI) and coordinated by the International Agency for Research on Cancer (IARC), is to promote and sustain collaboration and pooling of data to investigate the association between a wide range of agricultural exposures and a wide range of health outcomes, with a particular focus on associations that cannot easily be addressed in individual studies because of rare exposures (e.g., use of infrequently applied chemicals) or relatively rare outcomes (e.g., certain types of cancer, neurologic and auto-immune diseases). To facilitate future projects the need for data harmonization of selected variables is required and is underway. Altogether, AGRICOH provides excellent opportunities for studying cancer, respiratory, neurologic, and auto-immune diseases as well as reproductive and allergic disorders, injuries and overall mortality in association with a wide array of exposures, prominent among these the application of pesticides. © 2011 by the authors.
Early Toxic Effects in a Central American Native Fish (Parachromis dovii) Exposed to Chlorpyrifos and Difenoconazole
(Society of Environmental Toxicology and Chemistry, 2021-03-18) Jiménez, Katherine; Solano, Karla; Scholz, Carola; Redondo López, Sergei; Mena, Freylan
In Costa Rica, agriculture is one of the most important economic activities. Chlorpyrifos and difenoconazole have been identified as agrochemicals widely used in banana and pineapple crops in the Caribbean area of the country and are constantly recorded in aquatic ecosystems. The toxicity of these pesticides in Parachromis dovii was studied. Median lethal concentrations (LC50s) for each substance were obtained from 96‐h acute tests. Then, fish were exposed to sublethal concentrations of both substances (10% of LC50), individually and in mixture, to evaluate biomarker responses. Ethoxyresorufin‐O‐deethylase (EROD), catalase, and glutathione S‐transferase activities as well as lipid peroxidation were measured in liver and gill tissues as markers of biotransformation and oxidative stress processes. Cholinesterase activity in brain and muscle tissue was also quantified as a biomarker of toxicity. The LC50s were 55.34 μg/L (95% confidence interval [CI] 51.06–59.98) for chlorpyrifos and 3250 μg/L (95% CI 2770–3810) for difenoconazole. Regarding the biomarkers, a significant inhibition of brain and muscle cholinesterase activity was recorded in fish exposed to 5.50 μg/L of chlorpyrifos. This activity was not affected when fish were exposed to the mixture of chlorpyrifos with difenoconazole. Significant changes in lactate dehydrogenase activity were observed in fish exposed to 325 μg/L of difenoconazole, whereas fish exposed to th mixture showed a significant increase in EROD activity in the liver. These results suggest harmful effects of chlorpyrifos insecticide at environmentally relevant concentrations. There is also evidence for an interaction of the 2 substances that affects the biotransformation metabolism at sublethal levels of exposure.
Social movements and risk perception: unions, churches, pesticides and bananas in Costa Rica
(International Journal of Occupational and Environmental Health, vol. 19, no. 1 2013, 2013-11-12) Jansen, Kees; van Wendel de Joode, Berna; Wesseling, Catharina; Barraza, Douglas
Background: Between 1992 and 2010 in the Costa Rican Caribbean, a social movement coalition called Foro Emau´s sought to change people’s view on problems of high pesticide use in banana production. Objective: To understand the formation and membership of Foro Emau´s, its success period, and its decline. Methods: Semi-structured interviews of 28 key actors; a questionnaire survey among school personnel (n5475) in Siquirres, Matina, and Talamanca counties; and secondary data from newspapers, leaflets, and movement documents were used. Results: Foro Emau´s developed activism around pesticide issues and put pressure on governmental agencies and banana companies and shaped people’s perception of pesticide risks. The success of the Foro Emau´s movement led to the reinforcement of a counteracting social movement (Solidarismo) by conservative sectors of the Catholic Church and the banana companies. We found that the participation of unions in Foro Emau´s is an early example of social movement unionism. Conclusions: Scientific pesticide risk analysis is not the only force that shapes emerging societal perceptions of pesticide risk. Social movements influence the priority given to particular risks and can be crucial in putting health and environmental risk issues on the political and research agenda.

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Examinando Artículos científicos por Materia "AGRICULTURAL CHEMICALS"