Estudio comparativo - Efectos cardiorrespiratorios, calidad y anestesia quirúrgica de xilacina /hidrato de cloral /ketamina versus xilacina /diazepán /ketamina en equinos.
Fecha
2007
Autores
Estrada McDermott, Juan M.
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Editor
Universidad Nacional, Costa Rica
Resumen
El propósito de este estudio fue determinar la seguridad cardiorrespiratoria y calidad de
la anestesia del protocolo xilacina /hidrato de cloral /ketamina comparado contra el
protocolo xilacina /diazepán /ketamina en la especie equina. Se monitorearon diversos
parámetros como frecuencia cardiaca, frecuencia respiratoria, presión arterial directa,
ECG, PaO2, PaCO2, exceso de base, Na, K, Ca y se tomó el tiempo para los periodos de
anestesia quirúrgica y recumbencia. Se obtuvo un promedio de 5 minutos más de
anestesia con xilacina /hidrato de cloral /ketamina (23.13minutos ± 2.59) comparado
con el protocolo xilacina /diazepán /ketamina (18.13 minutos ± 6.51) lo que da un valor
estadísticamente significativo de p<0,06, además de proveer un tiempo promedio de
recuperación de 36.25 minutos ± 11.52 contra 30,75 minutos ± 10.65 de la mezcla con
diazepán, sin diferencias estadísticamente significativas a nivel cardiovascular
(Promedio de la presión arterial para xilacina /hidrato de cloral /ketamina; Sistólica
115.100, Diastólica 81.788 y Media 95.488 contra Sistólica 133.873, Diastólica 98.937,
Media 114.357 del protocolo con diazepán), respiratorio y en el balance homeostático
de los pacientes. La inducción y la recuperación fueron filmadas para determinar la
seguridad de las técnicas obteniendo buenos resultados. En general se demostró que la
adición del hidrato de cloral a la xilacina y la ketamina provee una calidad de anestesia
deseada y un mayor tiempo de anestesia quirúrgica.
The purpose of this study was to determine the cardio-respiratory safety and the quality of the xilazine /chloral hydrate /ketamine protocol compared to xilazine /diazepam /ketamine in the horse. The monitored parameters were HR, RR, invasive blood pressure, ECG, base excess, PaO2, PaCO2, Na, K, Ca, and the times for surgical anaesthesia and recumbency. An average time of extra 5 minutes of surgical anaesthesia was obtained with xilazine /chloral hydrate /ketamina (23.13 minutes ± 2.59) compared to xilazine /diazepam /ketamina (18.13 minutes ± 6.51) with a significant statistical value of p<0,06, with recovery times of 30.25 minutes ± 11.52 for the chloral hydrate combination versus 30,75 minutes ± 10.65 for the diazepam one, without great cardiovascular variations (Average arterial blood pressure for xilazine /chloral hydrate /ketamina was Systolic 115.100, Diastolic 81.788 and Mean 95.488 versus Systolic 133.873, Diastolic 98.937 and Mean 114.357 for the diazepam protocol), respiratory and homeostatic balance of the patients. Induction and recovery were taped to determine the safety of the protocols with successful results. In the overall it was demonstrated that the usage of chloral hydrate in addition to xilazine and ketamina provides a desired quality of anaesthesia and a longer surgical anaesthesia period.
The purpose of this study was to determine the cardio-respiratory safety and the quality of the xilazine /chloral hydrate /ketamine protocol compared to xilazine /diazepam /ketamine in the horse. The monitored parameters were HR, RR, invasive blood pressure, ECG, base excess, PaO2, PaCO2, Na, K, Ca, and the times for surgical anaesthesia and recumbency. An average time of extra 5 minutes of surgical anaesthesia was obtained with xilazine /chloral hydrate /ketamina (23.13 minutes ± 2.59) compared to xilazine /diazepam /ketamina (18.13 minutes ± 6.51) with a significant statistical value of p<0,06, with recovery times of 30.25 minutes ± 11.52 for the chloral hydrate combination versus 30,75 minutes ± 10.65 for the diazepam one, without great cardiovascular variations (Average arterial blood pressure for xilazine /chloral hydrate /ketamina was Systolic 115.100, Diastolic 81.788 and Mean 95.488 versus Systolic 133.873, Diastolic 98.937 and Mean 114.357 for the diazepam protocol), respiratory and homeostatic balance of the patients. Induction and recovery were taped to determine the safety of the protocols with successful results. In the overall it was demonstrated that the usage of chloral hydrate in addition to xilazine and ketamina provides a desired quality of anaesthesia and a longer surgical anaesthesia period.
Descripción
Modalidad: Tesis
Palabras clave
CABALLOS, EQUINOS, CIRUGÍA VETERINARIA, VETERINARY SURGERY, ANESTESIA EN VETERINARIA, VETERINARY ANESTHESIA, PROTOCOLO