Caracterización molecular de dos brotes de distemper canino en animales de vida silvestre en Costa Rica
Fecha
2017
Autores
Jiménez Soto, Mauricio
Murcia, Pablo
Piche-Ovares, María Marta
Alfaro-Alarcon, Alejandro
Jiménez Sánchez, Carlos
Título de la revista
ISSN de la revista
Título del volumen
Editor
Universidad Nacional, Costa Rica
Resumen
El virus del distemper canino (CDV), es el causante de una importante enfermedad infecciosa que
afecta perros, cánidos de vida silvestre y otros carnívoros. Es altamente patógeno, pertenece al género
Morbillivirus, familia Paramyxoviridae; posee un ARN de polaridad negativa que codifica para seis
proteínas mayores. La hemaglutinina (H) y la proteína de fusión (F) son las responsables de la unión
y fusión con la célula. El gen H tiene la mayor variabilidad en todo el genoma, este gen se utiliza
para clasificar las diferentes cepas virales. El virus causa problemas respiratorios, gastrointestinales y
neurológicos en caninos de diferentes edades. En los últimos años se ha reportado un aumento de los
casos de CDV en animales tanto de vida silvestre, así como en animales domésticos con y sin esquema
completo de vacunación.
Canine distemper virus (CDV) is the cause of an important infectious disease affecting dogs, wild canids and other carnivores. It is highly pathogenic, belongs to the genus Morbillivirus, family Paramyxoviridae; it possesses a negative polarity RNA that codes for six major proteins. Hemagglutinin (H) and fusion protein (F) are responsible for binding and fusion with the cell. The H gene has the highest variability in the entire genome, this gene is used to classify the different viral strains. The virus causes respiratory, gastrointestinal and neurological problems in canines of different ages. In recent years, an increase in CDV cases has been reported in wildlife animals as well as in domestic animals with and without a complete vaccination schedule.
Canine distemper virus (CDV) is the cause of an important infectious disease affecting dogs, wild canids and other carnivores. It is highly pathogenic, belongs to the genus Morbillivirus, family Paramyxoviridae; it possesses a negative polarity RNA that codes for six major proteins. Hemagglutinin (H) and fusion protein (F) are responsible for binding and fusion with the cell. The H gene has the highest variability in the entire genome, this gene is used to classify the different viral strains. The virus causes respiratory, gastrointestinal and neurological problems in canines of different ages. In recent years, an increase in CDV cases has been reported in wildlife animals as well as in domestic animals with and without a complete vaccination schedule.
Descripción
Suplemento XXII Congreso Nacional de Medicina Veterinaria, Costa Rica, 2017
Palabras clave
COSTA RICA, VIROLOGIA VETERINARIA, VETERINARY VIROLOGY, VIDA SILVESTRE, WILDLIFE