Implementación de un protocolo para biopsia de corteza renal en caninos y felinos con enfermedad renal aguda y crónica, como complemento diagnóstico en el Laboratorio de Patología y el Hospital de Especies Menores y Silvestres (HEMS) de la Escuela de Medicina Veterinaria de la Universidad Nacional.
Fecha
2013-12-11
Autores
González Barrantes, Juan Carlos
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Universidad Nacional, Costa Rica
Resumen
Se utilizaron para el estudio 18 animales que tenían sintomatología que se podía
relacionar con enfermedad renal, se hicieron exámenes de laboratorio para llegar a un
diagnóstico clínico de enfermedad renal.
Se tomaron biopsias de riñón en estos animales, se evaluó al mismo tiempo la
efectividad de un protocolo farmacológico diseñado para este propósito.
Todas las muestras fueron diagnósticas, siendo calificadas como “buenas” el
44% de las muestras y como “regular” el 56% de las muestras. El 83% de los animales
que se les permitió recuperarse tuvo una recuperación “buena”, mientras que 17% tuvo
una recuperación “regular”. No se detectaron complicaciones por la toma de la biopsia
en ningún caso.
En todos los casos se emitió un diagnóstico histopatológico y un pronóstico, los
hallazgos histopatológicos coincidieron con el diagnóstico clínico en el 100% de los
casos. Sin embargo, se encontró que la biopsia de riñón brinda información sumamente
valiosa para el clínico, tiene mayor alcance diagnóstico y pronóstico que cualquiera de
las otras técnicas diagnósticas con un riesgo bajo.
Con los hallazgos de la biopsia se diseñó un plan terapéutico para los animales
con enfermedad renal, tomando en cuenta las complicaciones más frecuentes y su
respectivo tratamiento.
Se concluyó que la biopsia de riñón es una herramienta muy útil que puede
brindar información valiosa para el manejo individualizado de los casos de enfermedad
renal si se emplea correctamente, por lo que debería ser utilizada con mayor frecuencia
en la investigación clínica del tracto urinario.
In this study, 18 animals that had symptoms that could be related to kidney disease were evaluated, routine laboratory analysis were used to assign a clinical diagnosis of renal disease. Biopsy samples were obtained in these animals, at the same time, the effectiveness of a pharmacological protocol that was designed for this purpose was evaluated. Chemical restriction, sample quality, recovery times, and presence of complications were measured, qualifying these as “good”, “regular” and “poor”. All of the samples were of diagnostic value, 44% of them being qualified as “good” and 56% being qualified as “regular”. 83% of the animals that were allowed to recover had a “good” recovery, whilst 17% had a “regular” recovery. No complications were detected in any case. In every case a histopathological diagnosis and prognosis was ensued, these findings matched with the clinical diagnostic scores in 100% of the cases. However, it was found that the kidney biopsy yields information of great value for the clinician, and that it has far greater diagnostic and pronostic value than any of the other diagnostic techniques, and has a low risk. With the biopsy findings, a therapeutical plan was designed for animals with kidney disease taking into account the most frequent complications and their respective treatment. It was concluded that renal biopsy is in fact a useful tool that can yield valuable information for the individualized management of renal disease if used correctly, and so that it should be used more frequently in the clinical investigation of the urinary tract.
In this study, 18 animals that had symptoms that could be related to kidney disease were evaluated, routine laboratory analysis were used to assign a clinical diagnosis of renal disease. Biopsy samples were obtained in these animals, at the same time, the effectiveness of a pharmacological protocol that was designed for this purpose was evaluated. Chemical restriction, sample quality, recovery times, and presence of complications were measured, qualifying these as “good”, “regular” and “poor”. All of the samples were of diagnostic value, 44% of them being qualified as “good” and 56% being qualified as “regular”. 83% of the animals that were allowed to recover had a “good” recovery, whilst 17% had a “regular” recovery. No complications were detected in any case. In every case a histopathological diagnosis and prognosis was ensued, these findings matched with the clinical diagnostic scores in 100% of the cases. However, it was found that the kidney biopsy yields information of great value for the clinician, and that it has far greater diagnostic and pronostic value than any of the other diagnostic techniques, and has a low risk. With the biopsy findings, a therapeutical plan was designed for animals with kidney disease taking into account the most frequent complications and their respective treatment. It was concluded that renal biopsy is in fact a useful tool that can yield valuable information for the individualized management of renal disease if used correctly, and so that it should be used more frequently in the clinical investigation of the urinary tract.
Descripción
Modalidad: Práctica dirigida
Palabras clave
PERRO, FELINOS, RIÑONES, ENFERMEDADES EN GATOS, ENFERMEDADES CANINAS, BIOPSIA, PROTOCOLO, DIAGNOSTICO DE LABORATORIO