Now showing items 1423-1442 of 13291

    • Breve recorrido por algunas características de la población ngöbe-buglé en el Territorio Indígena de Coto Brus, Costa Rica 

      Rodríguez-Brenes, Sharon (2016-05-18)
      Esta infografía aborda principales problemáticas identificadas por el personal de salud, elementos representativos de las mujeres y los hombres ngöbe-buglé, elementos que denotan el inicio de la vida sexual, cuidados ...
    • Breve reflexiones sobre el movimiento estudiantil en América Latina 

      Mata Rivera, Enrique (Centro de Estudios Generales, Universidad Nacional, Costa Rica, 2010-09)
      Los movimientos estudiantiles han sido un fenómeno constante a lo largo de la historia de nuestro continente desde el período colonial, y con una mayor presencia en la realidad latinoamericana a partir del movimiento en ...
    • Bringing critical discourse analysis into the foreign language classroom: a case study of a Taiwanese learner of spanish in Costa Rica 

      Loaiza Berrocal, Mayra; Madrigal Villegas, Vera; Vargas Barquero, Vivian (Universidad Nacional, Costa Rica, 2016-01)
      Esta investigación promueve la implementación del análisis del discurso a partir de un estudio de caso de un estudiante taiwanés del español como lengua extranjera. Por otra parte, este estudio señala la necesidad de incluir ...
    • Brown rats (Rattus norvegicus) in urban ecosystems: are the constraints related to fieldwork a limit to their study? 

      Desvars Larrive, Amélie; Walter, Theresa; Zink, Richard; Walzer, Chris; Baldi, Mario (Springer, 2018-07-05)
      Nowadays, the majority of human beings live in urban ecosystems, with this proportion expected to continue increasing in the future. With the growing importance of urban rat-associated issues (e.g. damages to urban ...
    • Brucella abortus induces the premature death of human neutrophils through the action of Its lipopolysaccharide 

      Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS; Mora-Cartín, Ricardo; Arce-Gorvel, Vilma; de Diego, Juana L.; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Buret, Andre; Gorvel, Jean-Pierre; Moreno, Edgardo (PLoS Pathogens, 2015-05-06)
      Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ...
    • Brucella abortus lipopolysaccharide in murine peritoneal macrophages acts as a down-regulator of T cell activation 

      Forestier, Claire; Deleuil, Fabienne; Lapaque, Nicolas; Gorvel, Jean Pierre; Moreno, Edgardo (The American Association of Immunologists, Inc., 2000)
      Macrophages play a central role in host immune responses against pathogens by acting as both professional phagocytic cells and as fully competent APCs. We report here that the LPS from the facultative intracellular ...
    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios-Chaves, Leyre; Conde-Álvarez, Raquel; Gil-Ramírez, Yolanda; Zúñiga-Ripa, Amaia; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Arce-Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; de Miguel, María-Jesús; Grilló, María-Jesús; Moriyon, Ignacio; Iriarte, Maite (PLoS One, 2011-01-07)
      The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...
    • Brucella abortus S19 GFP-tagged vaccine allows the serological identification of vaccinated cattle 

      Chacón-Díaz, Carlos; Zabalza-Baranguá, Ana; San Román, Beatriz; Blasco, Jose-María; Iriarte, Maite; Salas-Alfaro, Dariana; Hernández-Mora, Gabriela; BARQUERO-CALVO, ELIAS; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; Grillo, María Jesús; Moreno, Edgardo (PLOS ONE, 2021-11-22)
      Bovine brucellosis induces abortion in cows, produces important economic losses, and causes a widely distributed zoonosis. Its eradication was achieved in several countries after sustained vaccination with the live ...
    • Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich 

      Altamirano-Silva, Pamela; Meza-Torres, Jazmín; Castillo-Zeledón, Amanda; Ruiz-Villalobos, Nazareth; Zúñiga Pereira, Ana Mariel; Chacón-Díaz, Carlos; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology., 2018-01-16)
      Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...
    • Brucella abortus strain 2308 Wisconsin genome: Importance of the definition of reference strains 

      Castillo-Zeledón, Amanda; Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Roop, R. Martin; Comerci, Diego J.; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Caswell, Clayton C.; Baker, Kate; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; LETESSON, Jean-Jacques; De Bolle, Xavier; Guzman-Verri, Caterina (Frontiers in Microbiology, 2016-09-29)
      La brucelosis es una enfermedad infecciosa bacteriana que afecta a una amplia gama de mamíferos y una zoonosis desatendida causada por especies del género genéticamente homogéneo Brucella. Como en la mayoría de los estudios ...
    • Brucella abortus transits through the autophagic pathway and replicates in the endoplasmic reticulum of nonprofessional phagocytes 

      PIZARRO CERDA, JAVIER; MERESSE, STEPHANE; PARTON, ROBERT; GISOU, VAN DER; SOLA LANDA, ALBERTO; LOPEZ GOÑI, IGNACIO; GORVEL, JEAN PIERRE; Moreno, Edgardo (American Society for Microbiology, 1988-09-01)
      Brucella abortus is an intracellular pathogen that replicates within a membrane-bounded compartment. In this study, we have examined the intracellular pathway of the virulent B. abortus strain 2308 (S2308) and the attenuated ...
    • Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection 

      BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Weiss, David; Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Rucavado, Alexandra; Moriyon, Ignacio; Moreno, Edgardo (PLOS ONE, 2007-07-18)
      Background. To unravel the strategy by which Brucella abortus establishes chronic infections, we explored its early interaction with innate immunity. Methodology/Principal Findings. Brucella did not induce proinflammatory ...
    • Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts 

      Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Altamirano-Silva, Pamela; González-Espinoza, Gabriela; Medina, María-Concepción; Alfaro-Alarcón, Alejandro; Bouza-Mora, Laura; Jiménez-Rojas, César; Wong, Melissa; BARQUERO-CALVO, ELIAS; Rojas, Norman; Moreno, Edgardo; Chaves-Olarte, Esteban (Infection and Immunity, 2015-09-29)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...
    • Brucella ceti and brucellosis in cetaceans 

      Guzman-Verri, Caterina; González-Barrientos, Rocio; Hernández-Mora, Gabriela; Morales, Juan Alberto; BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Moreno, Edgardo (Frontiers in cellular and infection microbiology, 2012-02-06)
      Since the first case of brucellosis detected in a dolphin aborted fetus, an increasing number of Brucella ceti isolates has been reported in members of the two suborders of cetaceans: Mysticeti and Odontoceti. Serological ...
    • Brucella ceti infection in dolphins from the Western Mediterranean sea 

      Guzman-Verri, Caterina; Isidoro Ayza, Marcos; Ruiz-Villalobos, Nazareth; Pérez, Lola; Muñoz, Pilar M.; Alegre, Fernando; Barberán, Montserrat; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Gonzalez-Barrientos, Rocio; Moreno, Edgardo; Blasco, José María; Domingo, Mariano (Frontiers in cellular and infection microbiology, 2012)
      Background: Brucella ceti infections have been increasingly reported in cetaceans. Brucellosis in these animals is associated with meningoencephalitis, abortion, discospondylitis', subcutaneous abscesses, endometritis and ...
    • Brucella evades macrophage killing via VirB-dependent sustained interactions with the endoplasmic reticulum 

      Celli, Jean; Chastellier, Chantal de; Franchini, Don Marc; Pizarro Cerda, Javier; Gorvel, Jean Pierre; Moreno, Edgardo (The Rockefeller University Press, 2003-01-18)
      The intracellular pathogen Brucella is the causative agent of brucellosis, a worldwide zoonosis that affects mammals, including humans. Essential to Brucella virulence is its ability to survive and replicate inside host ...
    • Brucella evolution and taxonomy 

      Cloeckaertb, Axel; Moriyon, Ignacio; Moreno, Edgardo (Elsevier Science B.V, 2002)
      The genus Brucella contains alpha-Proteobacteria adapted to intracellular life within cells of a variety of mammals. Controversy has arisen concerning Brucella internal taxonomy, and it has been proposed that the DNA–DNA ...
    • Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution 

      Suárez-Esquivel, Marcela; Baker, Kate; Ruiz-Villalobos, Nazareth; Hernandez-Mora, Gabriela; BARQUERO-CALVO, ELIAS; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
      Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...
    • Brucella genomics: macro and micro evolution 

      Guzman-Verri, Caterina; Suárez-Esquivel, Marcela; Chaves Olarte, Esteban; Moreno, Edgardo (MDPI AG, 2020-10-20)
      Brucella organisms are responsible for one of the most widespread bacterial zoonoses, named brucellosis. The disease affects several species of animals, including humans. One of the most intriguing aspects of the brucellae ...
    • Brucella melitensis: a nasty bug with hidden credentials for virulence 

      Moreno, Edgardo; Moriyón, Ignacio (The National Academy of Sciences, 2002-01-08)
      On September 23, 1905, a cargo carrying 60 goats from Malta arrived in New York. The herd was kept in quarantine because of several deaths that occurred during the journey. Crewmen, an agent from the U.S. Bureau of Animal ...