Examinando por Autor "Cerecetto, Hugo"

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Biorefinery of Rice Husk to Obtain Functionalized Bioactive Compounds
(Tech Science Press (Estados Unidos), 2019) Lopretti, M.; Lecot, Nicole; Rodriguez, A.; Lluberas, G.; Orozco, F.; Bolaños, L.; Montes De Oca, G.; Cerecetto, Hugo; Jose-Roberto, Vega-Baudrit
The biomass industrialization valorisation of grains and cereals is considered an opportunity for the countries where agro-industrial activity is one of its main economic activities, rendering new higher-value products with a concomitant solution to waste accumulation issues. To that end, in this work we describe and characterise bioactive compounds generation from rice husk by semi-solid fermentation, obtained from 500 g of the material at room temperature and 60% humidity with mixed cultures of Phanerochaete chrysosporium and Gloeophyllum trabeum. The extract was evaluated in different situations: murine mammary tumour cells (4T1), normal cells (NIH 3T3) and in Lactobacillus acidophilus, and Trichoderma harzianum. The results exhibited that the extract inhibited 4T1 cells at concentrations higher than 20μg/mL, but did not inhibit normal cells, and displayed germicide activity after 3 days incubations. We propose that these functionalized compounds have a potential application in industry/agriculture/medicine obtained from rice husk waste.