Browsing Facultad de Ciencias de la Tierra y el Mar by Author "Mergler, Donna"
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Aerial application of mancozeb and urinary ethylene thiourea (ETU) concentrations among pregnant women in Costa Rica: the Infants' Environmental Health Study (ISA)
van Wendel de Joode, Berna; Mora, Ana Maria; Cordoba, Leonel; Cano, Juan Camilo; Quesada, Rosario; Faniband, Moosa; Wesseling, Catharina; Ruepert, Clemens; Öberg, Mattias; Eskenazi, Brenda; Mergler, Donna; Lindh, Christian (Environmental Health Perspectives, 2014-12-01)Background: Mancozeb and its main metabolite ethylene thiourea (ETU) may alter thyroid function; thyroid hormones are essential for fetal brain development. In Costa Rica, mancozeb is aerially sprayed at large-scale banana ... -
Aerial application of mancozeb and urinary ethylene thiourea (ETU) concentrations among pregnant women in Costa Rica: the Infants' Environmental Health Study (ISA).
van Wendel de Joode, Berna; Mora, Ana María; Córdoba, Leonel; Cano, Camilo; Quesada, Rosario; Faniband, Moosa; Wesseling, Catharina; Ruepert, Clemens; Oberg, Mathias; Eskenazi, Brenda; Mergler, Donna; Lindh, Christian (Research: Children´s health, 2014-12)Background: Mancozeb and its main metabolite ethylene thiourea (ETU) may alter thyroid function; thyroid hormones are essential for fetal brain development. In Costa Rica, mancozeb is aerially sprayed at large-scale ... -
Blood and hair manganese concentrations in pregnant women from the infants' environmental health study (ISA) in Costa Rica
Mora, Ana María; van Wendel de Joode, Berna; Mergler, Donna; Córdoba, Leonel; Cano, Camilo; Quesada, Rosario; Smith, Donald R; Lindh, Christian H; Bradman, Asa; Eskenazi, Brenda; Menezes-Filho, José A.; Lundh, Thomas (American Chemical Society, 2014-03)Manganese (Mn), an essential nutrient, is a neurotoxicant at high concentrations. We measured Mn concentrations in repeated blood and hair samples collected from 449 pregnant women living near banana plantations with ... -
Indigenous children living nearby plantations with chlorpyrifos-treated bags have elevated 3,5,6-trichloro-2-pyridinol (TCPy) urinary concentrations
van Wendel de Joode, Berna; Barraza, Douglas; Ruepert, Clemens; Mora Vargas, Ana Maria; Oberg, Mathias; Wesseling, Catharina; Lindh, Christian; Mergler, Donna; Córdoba, Leonel (Elsevier, 2012)The US Environmental Protection Agency voluntary phased-out residential use of chlorpyrifos in 2001. In contrast, in Costa Rica, chlorpyrifos-treated bags are increasingly used to protect banana and plantain fruits from ... -
Manganese concentrations in drinking water from villages near banana plantations with aerial mancozeb spraying in Costa Rica: Results from the Infants' Environmental Health Study (ISA)
van Wendel de Joode, Berna; Barbeau, Benoit; Bouchard, Maryse; Mora, Ana María; Skytt, Asa; Córdoba, Leonel; Quesada, Rosario; Lundh, Thomas; Lindh, Christian; Mergler, Donna (Elsevier, 2016-03)Elevated manganese (Mn) in drinking water has been reported worldwide. While, naturally occurring Mn in groundwater is generally the major source, anthropogenic contamination by Mn-containing fungicides such as mancozeb ... -
Maternal blood and hair manganese concentrations, fetal growth, and length of gestation in the ISA cohort in Costa Rica
Mora, Ana Maria; van Wendel de Joode, Berna; Mergler, Donna; Cordoba, Leonel; Cano, Camilo; Quesada, Rosario; Smith, Donald R.; Menezes-Filho, José; Eskenazi, Brenda (Environmental Research, 2015-01)Background: Animal studies have shown that both deficiency and excess manganese (Mn) may result in decreased fetal size and weight, but human studies have reported inconsistent results. Methods: We examined the association ... -
Maternal blood and hair manganese concentrations, fetal growth, and length of gestation in the ISA cohort in Costa Rica
Mora, Ana María; van Wendel de Joode, Berna; Mergler, Donna; Córdoba, Leonel; Cano, Camilo; Quesada, Rosario; Smith, Donald R; Menezes-Filho, José A.; Eskenazi, Brenda (Elsevier, 2015)Background: Animal studies have shown that both deficiency and excess manganese (Mn) may result in decreased fetal size and weight, but human studies have reported inconsistent results. Methods: We examined the association ... -
Pesticide exposure and neurodevelopment in children age 6-9 years from Talamanca, Costa Rica.
van Wendel de Joode, Berna; Mora, Ana María; Lindh, Christian; Hernández Bonilla, David; Córdoba, Leonel; Wesseling, Catharina; Hoppin, Jane; Mergler, Donna (Elsevier Ltd, 2016-09-05)Certain pesticides may affect children's neurodevelopment. We assessed whether pesticide exposure was associated with impaired neurobehavioral outcomes in children aged 6e9 years. We conducted a cross-sectional study ... -
Prenatal mancozeb exposure, excess manganese, and neurodevelopment at 1 year of age in the Infants' Environmental Health (ISA) study
Mora, Ana Maria; Cordoba, Leonel; Cano, Juan C.; Hernandez-Bonilla, David; Pardo, Larissa; Smith, Donald R.; Menezes-Filho, José A.; Mergler, Donna; Lindh, Christian H.; Eskenazi, Brenda; van Wendel de Joode, Berna; Schnaas, Lourdes (Environmental Health Perspectives, 2018-05-29)BACKGROUND: Although growing evidence suggests that early-life excess manganese (Mn) impairs neurodevelopment, data on the neurodevelopmental effects of mancozeb, a fungicide containing Mn, and its main metabolite ... -
Volumen #12: Factores determinantes de las concentraciones maternas de manganeso durante el embarazo, y su asociación con el crecimiento fetal en la cohorte Infantes y Salud Ambiental (ISA) en Costa Rica
Mora, An; Berna van Wendel de, Joode; Mergler, Donna; Córdoba, Leonel; Cano, Camilo; Donald, Smith; Menezes, José; Lundh, Thomas; Lindh, Christian; Asa, Bradman; Eskenazi, Brenda (SALTRA / IRET-UNA, 2015-04-01)Resumen de los resultados \nLos fungicidas etilenobisditiocarbamatos (EBDC, por sus siglas en inglés) mancozeb y maneb contienen cantidades sustanciales de Mn (21% en peso) y, consecuentemente, pueden constituir una fuente ...