Facultad de Ciencias de la Salud: Recent submissions

Now showing items 841-860 of 1554

    • BvrR/BvrS-controlled outer membrane proteins Omp3a and Omp3b are not essential for Brucella abortus virulence 

      Manterola, Lorea; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; BARQUERO-CALVO, ELIAS; de Miguel, María-Jesús; Moriyon, Ignacio; Grillo, María-Jesús; López-Goñi, Ignacio; Moreno, Edgardo (American Society for Microbiology, 2007-07-30)
      The Brucella abortus two-component regulatory system BvrR/BvrS controls the expression of outer membrane proteins (Omp) Omp3a (Omp25) and Omp3b (Omp22). Disruption of bvrS or bvrR generates avirulent mutants with altered ...

    • Neurobrucellosis in stranded dolphins, Costa Rica 

      Hernández-Mora, Gabriela; González-Barrientos, Rocio; Morales, Juan Alberto; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS; De-Miguel, María-Jesús; Marín, Clara-María; Blasco, Jose-María; Moreno, Edgardo (Universidad Nacional, Costa Rica, 2008-09)
      Ten striped dolphins, Stenella coeruleoalba, stranded along the Costa Rican Pacifi c coast, had meningoencephalitis and antibodies against Brucella spp. Brucella ceti was isolated from cerebrospinal fl uid of 6 dolphins ...

    • Intracellular adaptation of Brucella abortus 

      Lamontagne, Julie; Forest, Anik; Marazzo, Elena; François, Denis; Butler, Heather; Michaud, Jean-François; Boucher, Lyne; Pedro, Ida; Villeneuve, Annie; Sitnikov, Dmitri; Trudel, Sylvie; Nassif, Najib; Boudjelt, Djamila; Tomaki, Fadi; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Brunet, Sylvain; Côté-Martin, Alexandra; Hunter, Joanna; Moreno, Edgardo; Paramithiotis, Eustache (Universidad Nacional, Costa Rica, 2009-03)
      Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially ...

    • Serological diagnosis of brucella infections in odontocetes 

      Hernández-Mora, Gabriela; Manire, Charles A.; González-Barrientos, Rocío; BARQUERO-CALVO, ELIAS; Guzman-Verri, Caterina; Staggs, Lydia; Thompson, Rachel; Chaves-Olarte, Esteban; Moreno, Edgardo (American Society for Microbiology, 2009-04-15)
      Brucella ceti causes disease in Odontoceti. The absence of control serum collections and the diversity of cetaceans have hampered the standardization of serological tests for the diagnosis of cetacean brucellosis. Without ...

    • The role of neutrophils in Brucellosis 

      BARQUERO-CALVO, ELIAS; Moreno, Edgardo (American Society for Microbiology, 2020-10-14)
      Brucellosis is a bacterial disease of domestic animals and humans. The pathogenic ability of Brucella organisms relies on their stealthy strategy and their capacity to replicate within host cells and to induce long-lasting ...

    • The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens 

      BARQUERO-CALVO, ELIAS; Conde-Álvarez, Raquel; Chacón-Díaz, Carlos; Quesada-Lobo, LucÍa; Martirosyan, Anna; Guzman-Verri, Caterina; Iriarte, Maite; Manček Keber, Mateja; Jerala, Roman; Gorvel, Jean-Pierre; Moriyon, Ignacio; Moreno, Edgardo; Chaves-Olarte, Esteban (PLOS ONE, 2009-06-16)
      Background: During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some a-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. ...

    • Pathology of striped dolphins (Stenella coeruleoalba) infected with Brucella ceti 

      González-Barrientos, Rocio; Morales, Juan Alberto; Hernández-Mora, Gabriela; BARQUERO-CALVO, ELIAS; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; Moreno, Edgardo (Elsevier Ltd, 2009-10-14)
      Seventeen striped dolphins (Stenella coeruleoalba) displaying swimming disorders compatible with neurological syndromes were investigated for Brucella infection. Sixteen dolphins had meningoencephalomyelitis. Serum antibody ...

    • The two-component system BvrR/BvrS regulates the expression of the Type IV secretion system VirB in Brucella abortus 

      Martínez-Núñez, Carola; Altamirano-Silva, Pamela; Alvarado-Guillén, Francisco; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology, 2010-11)
      The pathogenesis of Brucella is related to the ability to multiply intracellularly, an event controlled by the two-component system BvrR/BvrS (TCS BvrRS) and the type IV secretion machinery VirB (T4SS VirB). We have ...

    • The use of green fluorescent protein as a marker for Brucella vaccines 

      Chacón-Díaz, Carlos; Muñoz, Melissa; BARQUERO-CALVO, ELIAS; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; Grilló, María-Jesús; Moreno, Edgardo (Elsevier, 2010-11-04)
      La brucelosis es una importante enfermedad de los animales de producción y de la fauna silvestre y una zoonosis mundial. El uso de vacunas eficaces y las correspondientes pruebas de diagnóstico que permiten diferenciar los ...

    • Human Brucella melitensis infections in southern Vietnam 

      Campbell, J.I.; Lan, Nguyen Thi; Phuong, P.M.; Chau, L.B.; Pham, Trung Duc; Guzman-Verri, Caterina; Ruiz-Villalobos, Nazareth; Minh, T.P.T.; Muñoz Bruque, Álvaro; Moreno, Edgardo; Thwaites, G.E.; Rabaa, M.A.; Chau, N.V.V.; Bake, S. (European Society of Clinical Microbiology and Infectious Diseases, 2017-06-29)
      Brucellosis is a collective term for infections caused by small Gram-negative coccobacilli belonging to genus Brucella. This genus incorporates the well-described animal pathogens Brucella melitensis, Brucella abortus, ...

    • Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution 

      Suárez-Esquivel, Marcela; Baker, Kate; Ruiz-Villalobos, Nazareth; Hernandez-Mora, Gabriela; BARQUERO-CALVO, ELIAS; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
      Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...

    • Brucellosis in mammals of Costa Rica: an epidemiological survey 

      Hernández-Mora, Gabriela; Bonilla-Montoya, Roberto; Barrantes-Granados, Osvaldo; Esquivel-Suárez, Andrea; Montero-Caballero, Danilo; Fallas-Monge, Zeanne; Palacios Alfaro, Jose David; Baldi, Mario; Campos, Elena; Chanto, Grettel; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Romero-Zúñiga, Juan José; Moreno, Edgardo (PLOS ONE, 2017-08-09)
      La brucelosis ha sido una enfermedad endémica del ganado y los seres humanos en Costa Rica desde principios del siglo XX. Sin embargo, no se ha reportado brucelosis en ovejas, cabras, cerdos, búfalos de agua, caballos y ...

    • Inflencia del desnivel en la carga física del corredor de montaña: un estudio de caso 

      Gómez-Carmona, Carlos David; Bastida-Castillo, Alejandro; Rojas-Valverde, Daniel; Pino Ortega, José (Revista Internacional de Medicina y Ciencias de la Actividad Física y el Deporte, 2019)
      Este estudio analizó las exigencias de carga interna (Frecuencia cardíaca, FC) y externa (Velocidad; Player Load, PL; Power Metabolic, PM; Stiffness Vertical, Kvert; entropía aproximada, ApEn) que se producen en función ...

    • Intervención grupal para la modificación de hábitos alimentarios, composición corporal, actitud y conducta relacionada con el ejercicio físico, en mujeres adultas con sobre peso y obesidad mediante sesiones educativas y ejercicio aeróbico. Área de salud La Cruz, primer nivel de atención, CCSS 

      Retana Porras, Martha Iris (Universidad Nacional, Costa Rica, 2008)
      Determina el impacto que tiene una intervención grupal basada en sesiones educativas y de ejercicio aeróbico, con la participación de EBAIS de Santa Cecilia Central, en la modificación de hábitos alimentarios, composición ...

    • Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease 

      Hernández-Mora, Gabriela; Ruiz-Villalobos, Nazareth; Bonilla-Montoya, Roberto; Romero-Zúñiga, Juan José; Jiménez-Arias, Julio; González-Barrientos, Rocio; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Rojas, Norman; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Moreno, Edgardo (PLOS ONE, 2017-08-10)
      Brucellosis, caused by Brucella abortus is a major disease of cattle and a zoonosis. In order to estimate the bovine brucellosis prevalence in Costa Rica (CR), a total 765 herds (13078 bovines) from six regions of CR ...

    • Analysis of the association between density of Helicobacter spp and gastric lesions in dogs 

      Suárez-Esquivel, Marcela; Alfaro-Alarcón, Alejandro; Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS (American Journal of Veterinary Research, 2017-12)
      OBJECTIVE To evaluate the correlation between the density of native gastric Helicobacter spp and the presence of gastric lesions in dogs. ANIMALS 80 dogs of various breeds, sexes, and ages. PROCEDURES Gastroscopic and ...

    • Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich 

      Altamirano-Silva, Pamela; Meza-Torres, Jazmín; Castillo-Zeledón, Amanda; Ruiz-Villalobos, Nazareth; Zúñiga Pereira, Ana Mariel; Chacón-Díaz, Carlos; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology., 2018-01-16)
      Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...

    • Two groups of cocirculating, epidemic clostridiodes difficile strains microdiversify through different mechanisms 

      Murillo, Tatiana; Ramırez-Vargas, Gabriel; Riedel, Thomas; Overmann, Jörg; Andersen, Joakim; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; Rodrıguez, Cesar (Oxford University Press, 2018-03-14)
      Clostridiodes difficile strains from the NAPCR1/ST54 and NAP1/ST01 types have caused outbreaks despite of their notable differences in genome diversity. By comparing whole genome sequences of 32 NAPCR1/ST54 isolates and ...

    • Genetic and phenotypic characterization of the etiological agent of canine orchiepididymitis smooth Brucella sp. BCCN84.3 

      Guzman-Verri, Caterina; Suárez-Esquivel, Marcela; Ruíz-Villalobos, Nazareth; Zygmunt, Michel S.; Gonnet, Mathieu; Campos, Elena; Víquez-Ruiz, Eunice; Chacón-Díaz, Carlos; Aragón-Aranda, Beatriz; Conde-Álvarez, Raquel; Moriyon, Ignacio; Blasco, Jose-María; Muñoz, Pilar M.; Baker, Kate; Thomson, Nicholas; Cloeckaert, Axel; Moreno, Edgardo (Frontiers in Veterinary Science, 2019-06-07)
      Members of the genus Brucella cluster in two phylogenetic groups: classical and non-classical species. The former group is composed of Brucella species that cause disease in mammals, including humans. A Brucella species, ...

    • Combined electrokinetic manipulations of pathogenic bacterial samples in low-cost fabricated dielectrophoretic devices 

      Martinez-Brenes, Alejandro; Torres-Castro, Karina; Marín-Benavides, Richard; Acuña-Umaña, Katherine; Espinoza Araya, Christopher; Ramírez-Carranza, Raquel; González-Espinoza, Gabriela; Rojas-Campos, Norman; Guzman-Verri, Caterina; Sáenz-Arce, Giovanni; Lesser-Rojas, Leonardo (AIP Advances, 2019-11-13)
      A low-cost fabrication method of microfluidic devices with micrometer-sized constrictions used for electrodeless dielectrophoresis (eDEP) is demonstrated here. A structure on a commercial printed circuit board (PCB) ...