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Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease
(PLOS ONE, 2017-08-10)
Brucellosis, caused by Brucella abortus is a major disease of cattle and a zoonosis. In order
to estimate the bovine brucellosis prevalence in Costa Rica (CR), a total 765 herds (13078
bovines) from six regions of CR ...
Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich
(American Society for Microbiology., 2018-01-16)
Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...
Brucellosis in mammals of Costa Rica: an epidemiological survey
(PLOS ONE, 2017-08-09)
La brucelosis ha sido una enfermedad endémica del ganado y los seres humanos en Costa Rica desde principios del siglo XX. Sin embargo, no se ha reportado brucelosis en ovejas, cabras, cerdos, búfalos de agua, caballos y ...
Genetic and phenotypic characterization of the etiological agent of canine orchiepididymitis smooth Brucella sp. BCCN84.3
(Frontiers in Veterinary Science, 2019-06-07)
Members of the genus Brucella cluster in two phylogenetic groups: classical and
non-classical species. The former group is composed of Brucella species that cause
disease in mammals, including humans. A Brucella species, ...
Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution
(Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...
The use of green fluorescent protein as a marker for Brucella vaccines
(Elsevier, 2010-11-04)
La brucelosis es una importante enfermedad de los animales de producción y de la fauna silvestre y una zoonosis mundial. El uso de vacunas eficaces y las correspondientes pruebas de diagnóstico que permiten diferenciar los ...
The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens
(PLOS ONE, 2009-06-16)
Background: During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some a-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. ...
Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection
(PLOS ONE, 2007-07-18)
Background. To unravel the strategy by which Brucella abortus establishes chronic infections, we explored its early interaction with innate immunity. Methodology/Principal Findings. Brucella did not induce proinflammatory ...
Bacterial counts in spleen
(Bio-protocol, 2013-11-05)
Bacterial loads can be determined as colony forming units (CFU) at any point of the infection by culturing spleen homogenates on agar plates. This is a reliable method for comparing the kinetics of infection in various ...
Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern
(PLoS One, 2011-01-07)
The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...