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Now showing items 11-20 of 34
What have we learned from brucellosis in the mouse model?
(Veterinary Research, 2012)
Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by
practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...
N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils
(Universidad Nacional, Costa Rica, 2016-06)
Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ...
The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition
(PLoS Pathogens, 2012-05-10)
Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
Brucella β 1,2 cyclic glucan is an activator of human and mouse dendritic cells
(PLoS Pathogens, 2012-11-15)
Bacterial cyclic glucans are glucose polymers that concentrate within the periplasm of alpha-proteobacteria. These molecules are necessary to maintain the homeostasis of the cell envelope by contributing to the osmolarity ...
Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus
(PLoS Pathogens, 2013-02-14)
Polymorphonuclear neutrophils (PMNs) are the first line of defense against microbial pathogens. In addition to their role in innate immunity, PMNs may also regulate events related to adaptive immunity. To investigate the ...
Epidemiology of bovine brucellosis in Costa Rica: Lessons learned from failures in the control of the disease
(PLOS ONE, 2017-08-10)
Brucellosis, caused by Brucella abortus is a major disease of cattle and a zoonosis. In order
to estimate the bovine brucellosis prevalence in Costa Rica (CR), a total 765 herds (13078
bovines) from six regions of CR ...
Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich
(American Society for Microbiology., 2018-01-16)
Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...
Brucellosis in mammals of Costa Rica: an epidemiological survey
(PLOS ONE, 2017-08-09)
La brucelosis ha sido una enfermedad endémica del ganado y los seres humanos en Costa Rica desde principios del siglo XX. Sin embargo, no se ha reportado brucelosis en ovejas, cabras, cerdos, búfalos de agua, caballos y ...
Genetic and phenotypic characterization of the etiological agent of canine orchiepididymitis smooth Brucella sp. BCCN84.3
(Frontiers in Veterinary Science, 2019-06-07)
Members of the genus Brucella cluster in two phylogenetic groups: classical and
non-classical species. The former group is composed of Brucella species that cause
disease in mammals, including humans. A Brucella species, ...
Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution
(Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...