Browsing Facultad de Ciencias de la Salud by Author "Chacón-Díaz, Carlos"

Now showing items 1-20 of 26

    • Bacterial counts in spleen 

      BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Moreno, Edgardo (Bio-protocol, 2013-11-05)
      Bacterial loads can be determined as colony forming units (CFU) at any point of the infection by culturing spleen homogenates on agar plates. This is a reliable method for comparing the kinetics of infection in various ...

    • Brucella abortus induces the premature death of human neutrophils through the action of Its lipopolysaccharide 

      Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS; Mora-Cartín, Ricardo; Arce-Gorvel, Vilma; de Diego, Juana L.; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Buret, Andre; Gorvel, Jean-Pierre; Moreno, Edgardo (PLoS Pathogens, 2015-05-06)
      Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ...

    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios-Chaves, Leyre; Conde-Álvarez, Raquel; Gil-Ramírez, Yolanda; Zúñiga-Ripa, Amaia; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Arce-Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; de Miguel, María-Jesús; Grilló, María-Jesús; Moriyon, Ignacio; Iriarte, Maite (PLoS One, 2011-01-07)
      The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...

    • Brucella abortus S19 GFP-tagged vaccine allows the serological identification of vaccinated cattle 

      Chacón-Díaz, Carlos; Zabalza-Baranguá, Ana; San Román, Beatriz; Blasco, Jose-María; Iriarte, Maite; Salas-Alfaro, Dariana; Hernández-Mora, Gabriela; BARQUERO-CALVO, ELIAS; Guzman-Verri, Caterina; Chaves-Olarte, Esteban; Grillo, María Jesús; Moreno, Edgardo (PLOS ONE, 2021-11-22)
      Bovine brucellosis induces abortion in cows, produces important economic losses, and causes a widely distributed zoonosis. Its eradication was achieved in several countries after sustained vaccination with the live ...

    • Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich 

      Altamirano-Silva, Pamela; Meza-Torres, Jazmín; Castillo-Zeledón, Amanda; Ruiz-Villalobos, Nazareth; Zúñiga Pereira, Ana Mariel; Chacón-Díaz, Carlos; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology., 2018-01-16)
      Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...

    • Brucella abortus strain 2308 Wisconsin genome: Importance of the definition of reference strains 

      Castillo-Zeledón, Amanda; Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Roop, R. Martin; Comerci, Diego J.; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Caswell, Clayton C.; Baker, Kate; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; LETESSON, Jean-Jacques; De Bolle, Xavier; Guzman-Verri, Caterina (Frontiers in Microbiology, 2016-09-29)
      La brucelosis es una enfermedad infecciosa bacteriana que afecta a una amplia gama de mamíferos y una zoonosis desatendida causada por especies del género genéticamente homogéneo Brucella. Como en la mayoría de los estudios ...

    • Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection 

      BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Weiss, David; Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Rucavado, Alexandra; Moriyon, Ignacio; Moreno, Edgardo (PLOS ONE, 2007-07-18)
      Background. To unravel the strategy by which Brucella abortus establishes chronic infections, we explored its early interaction with innate immunity. Methodology/Principal Findings. Brucella did not induce proinflammatory ...

    • Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts 

      Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Altamirano-Silva, Pamela; González-Espinoza, Gabriela; Medina, María-Concepción; Alfaro-Alarcón, Alejandro; Bouza-Mora, Laura; Jiménez-Rojas, César; Wong, Melissa; BARQUERO-CALVO, ELIAS; Rojas, Norman; Moreno, Edgardo; Chaves-Olarte, Esteban (Infection and Immunity, 2015-09-29)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...

    • Brucella ceti infection in dolphins from the Western Mediterranean sea 

      Guzman-Verri, Caterina; Isidoro Ayza, Marcos; Ruiz-Villalobos, Nazareth; Pérez, Lola; Muñoz, Pilar M.; Alegre, Fernando; Barberán, Montserrat; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Gonzalez-Barrientos, Rocio; Moreno, Edgardo; Blasco, José María; Domingo, Mariano (Frontiers in cellular and infection microbiology, 2012)
      Background: Brucella ceti infections have been increasingly reported in cetaceans. Brucellosis in these animals is associated with meningoencephalitis, abortion, discospondylitis', subcutaneous abscesses, endometritis and ...

    • Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution 

      Suárez-Esquivel, Marcela; Baker, Kate; Ruiz-Villalobos, Nazareth; Hernandez-Mora, Gabriela; BARQUERO-CALVO, ELIAS; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
      Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...

    • Brucella neotomae infection in humans, Costa Rica 

      BARQUERO-CALVO, ELIAS; Baker, Kate S.; Amuy, Ernesto; Chaves-Olarte, Esteban; Thomson, Nicholas R.; Moreno, Edgardo; Guzman-Verri, Caterina; Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Víquez-Ruiz, Eunice; Rojas-Campos, Norman; Oviedo-Sánchez, Gerardo (Emerging Infectious Diseases, 2017-06)
      Several species of Brucella are known to be zoonotic, but B. neotomae infection has been thought to be limited to wood rats. In 2008 and 2011, however, B. neotomae was isolated from cerebrospinal fluid of 2 men with ...

    • Brucellosis caused by the wood rat pathogen Brucella Neotomae: two case reports 

      Arnuy, Ernesto; Rojas, Norman; Villalobos-Vindas, Juan M.; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Moreno, Edgardo (Journal of Medical Case Reports, 2017-12-19)
      Background: Brucellosis is a chronic bacterial disease caused by members of the genus Brucella. Among the classical species stands Brucella neotomae, until now, a pathogen limited to wood rats. However, we have identified ...

    • Brucellosis in mammals of Costa Rica: an epidemiological survey 

      Hernández-Mora, Gabriela; Bonilla-Montoya, Roberto; Barrantes-Granados, Osvaldo; Esquivel-Suárez, Andrea; Montero-Caballero, Danilo; Fallas-Monge, Zeanne; Palacios Alfaro, Jose David; Baldi, Mario; Campos, Elena; Chanto, Grettel; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Romero-Zúñiga, Juan José; Moreno, Edgardo (PLOS ONE, 2017-08-09)
      La brucelosis ha sido una enfermedad endémica del ganado y los seres humanos en Costa Rica desde principios del siglo XX. Sin embargo, no se ha reportado brucelosis en ovejas, cabras, cerdos, búfalos de agua, caballos y ...

    • Comamonas testosteroni as the cause of mortality in embryonated chicken eggs of breeding broiler hens in Costa Rica 

      Chaves-Hernandez, Aida Jeannette; BARQUERO-CALVO, ELIAS; Quesada-Vasquez, Dioney; Chacón-Díaz, Carlos (Taylor and Francis Group, 2023-12)
      Mortality of chicken embryos andfirst-week chickens was reported in a commercial incubatorcompany in Costa Rica. Six 1-day-old Cobb chickens and twenty-four embryonated chickeneggs were examined in the Laboratory of Avian ...

    • Depletion of complement enhances the clearance of Brucella abortus in mice 

      González-Espinoza, Gabriela; BARQUERO-CALVO, ELIAS; Lizano-González, Esteban; Alfaro-Alarcón, Alejandro; Arias-Gómez, Berny; Chaves-Olarte, Esteban; Moreno, Edgardo; Lomonte, Bruno; Chacón-Díaz, Carlos (American Society for Microbiology, 2018-08-06)
      Brucellosis is a bacterial disease of animals and humans. Brucella abortus barely activates the innate immune system at the onset of infection, and this bacterium is resistant to the microbicidal action of complement. Since ...

    • If You're Not Confused, You're Not Paying Attention: Ochrobactrum Is Not Brucella 

      Moreno, Edgardo; Middlebrook, Earl A.; Altamirano-Silva, Pamela; Al Dahouk, Sascha; Araj, George F.; Arce-Gorvel, Vilma; Arenas-Gamboa, Ángela; Ariza, Javier; BARQUERO-CALVO, ELIAS; Battelli, Giorgio; Bertu, Wilson J.; Blasco, José María; Bosilkovsk, Mile; Cadmus, Simeon; Caswell, Clayton C.; Celli, Jean; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Comerci, Diego J.; Conde-Álvarez, Raquel; Cook, Elizabeth; Cravero, Silvio; Dadar, Maryam; De Boelle, Xavier; De Massis, Fabrizio; Díaz, Ramón; Escobar, Gabriela I.; Fernández-Lago, Luis; Ficht, Thomas A.; Foster, Jeffrey T.; Garin-Bastuji, Bruno; Godfroid, Jacques; Gorvel, Jean-Pierre; Güler, Leyla; Erdenlig-Gürbilek, Sevil; Gusi, Amayel M.; Guzman-Verri, Caterina; Hai, Jiang; Hernández-Mora, Gabriela; Iriarte, Maite; Jacob, Nestor R.; Keriel, Anne; Khames, Maamar; Köhler, Stephan; Letesson, Jean-Jacques; Loperena-Barber, Maite; López-Goñi, Ignacio; McGiven, John; Melzer, Falk; Mora-Cartin, Ricardo; Moran-Gilad, Jacob; Muñoz, Pilar M.; Neubauer, Heinrich; O'Callaghan, David; Ocholi, Reuben; Oñate, Ángel; Pandey, Piyush; Pappas, Georgios; Pembroke, J. Tony; Roop, Martin; Ruiz-Villalobos, Nazareth; Ryan, Michael P.; Salvador-Bescós, Miriam; Sangari, Félix J.; de Lima Santos, Renato; Seimenis, Aristarchos; Splitter, Gary; Suárez-Esquivel, Marcela; Tabbaa, Darem; Trangoni, Marcos David; Tsolis, Renee M.; Vizcaíno, Nieves; Wareth, Gamal; . Welburn, Susan C; Whatmore, Adrian; Zúñiga-Ripa, Amaia; Moriyónq, Ignacio (American Society for Microbiology, 2023-07-03)
      Bacteria of the genus Brucella are facultative intracellular parasites that cause brucellosis, a severe animal and human disease. Recently, a group of taxonomists merged the brucellae with the primarily free-living, ...

    • N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils 

      Mora-Cartín, Ricardo; Chacón-Díaz, Carlos; Gutiérrez-Jiménez, Cristina; Gurdián-Murillo, Stephany; Lomonte, Bruno; Chaves-Olarte, Esteban; BARQUERO-CALVO, ELIAS; Moreno, Edgardo (Universidad Nacional, Costa Rica, 2016-06)
      Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ...

    • Neutrophils as Trojan Horse vehicles for Brucella abortus macrophage infection 

      Gutiérrez-Jiménez, Cristina; Mora-Cartín, Ricardo; Altamirano-Silva, Pamela; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Moreno, Edgardo; BARQUERO-CALVO, ELIAS (Universidad Nacional, Costa Rica, 2019-05-07)
      Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ...

    • Neutrophils dampen adaptive immunity in Brucellosis 

      Mora-Cartín, Ricardo; Gutiérrez-Jiménez, Cristina; Alfaro-Alarcón, Alejandro; Chaves-Olarte, Esteban; Chacón-Díaz, Carlos; BARQUERO-CALVO, ELIAS; Moreno, Edgardo (American Society For Microbiology, 2019-04-23)
      Brucella organisms are intracellular stealth pathogens of animals and humans. The bacteria overcome the assault of innate immunity at early stages of an infection. Removal of polymorphonuclear neutrophils (PMNs) at the ...

    • Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis 

      Suárez-Esquivel, Marcela; Henández-Mora, Gabriela; Ruiz-Villalobos, Nazareth; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; LadnerI, JasonT.; Oviedo-Sánchez, Gerardo; Foster, JeffreyT.; Rojas-Campos, Norman; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (PLOS Neglected Tropical Diseases, 2020-04-14)
      Brucellosis, caused by Brucella abortus, is a major disease of cattle and humans worldwide distributed. Eradication and control of the disease has been difficult in Central and South America, Central Asia, the Mediterranean ...