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URI permanente para esta colecciónhttps://hdl.handle.net/11056/30769
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Ítem Fish cell lines as tools for ecotoxicological applications and replacement of whole-organism models. Is it necessary to develop lines from Neo-tropical species?(2024) Mena, Freylan.; Forzán, María J; Doherty, Alison; Blanco-Peña, KinndleCell cultures are adequate models to replace whole-animal assays in ecotoxicology and accomplish 3R and Onehealth objectives. The access to culture techniques should promote the development of cell lines representative of local ecosystems, especially considering the species-specific sensitivity that transcend in vivo models. Ecotoxicology laboratories should undertake the effort of developing and applying cellular models, especially the more complex 3D models, to improve their assessment methods.