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Facultad de Ciencias Exactas y Naturales

URI permanente para esta comunidadhttp://10.0.96.45:4000/handle/11056/14053

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Examinando Facultad de Ciencias Exactas y Naturales por Autor "Abarca, Gabriela"

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    An in vivo model to study the anti-malaric capacity of plant extracts
    (Universidad de Costa Rica, 1998) Chinchilla, Misael; Guerrero., OIga; Abarca, Gabriela; Barrios, , Mariano; Castro, Oscar
    An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30g body weight) are treated subcutaneously with 0.6ml of the diluted extract starting seven days before P. berghei infection; treatment continues until death or for 30 days. Simultaneously 0.2ml of the extract are applied per os starting three days before infection. In a test of the model, treated and non-treated animals differed in body weight, survival time, haematocrite, parasitemia development, and spleen or liver weight of recent dead or killed mice.