Browsing by Author "Garcia, Mario"
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A botanical extract of Souroubea sympetala and its active principle, betulinic acid, attenuate the cortisol response to a stressor in rainbow trout, Oncorhynchus mykiss
Mullally, Martha; Mimeault, Caroline; Otárola Rojas, Marco Antonio; Sanchez Vindas, Pablo; Garcia, Mario; Poveda Alvarez, Luis; Moon, Thomas W.; Gilmour, Kathleen M.; Trudeau, Vance; Arnason, John (Elsevier, 2016-09-28)The capacity of the traditional anxiolytic plant, Souroubea sympetala, and its bioactive principle, betulinic acid (BA), to lower cortisol levels in rainbow trout, Oncorhynchus mykiss, was investigated. Effects at the level ... -
A Selective Ion HPLC-APCI-MS Method for the Quantification of Pentacyclic Triterpenes in an Anxiolytic Botanical Dietary Supplement for the Animal Health Market
Liu, Rui; Carballo Arce, Ana Francis; Singh, Ranpreet; Saleem, Ammar ; Rocha, Marco; Mullally, Martha; Otarola-Rojas, Marco; Poveda Alvarrez, Luis; Sanchez-Vindas, Pablo; Garcia, Mario; Baker, John; Merali, Zul; Guerrero-Analco, José A.; Durst, Tony; Harris, Cory; Arnason, John (Natural Product Incorporation, 2019)A new anti-anxiety dietary supplement was developed for the animal health market, by combining 2 triterpene containing botanicals, Souroubea sympetala (Marcgraviaceae) with Platanus occidentalis (Platanaceae) A validated ... -
Antimicrobial activities of Marcgraviaceae species and isolation of a naphthoquinone from Marcgravia nervosa (Marcgraviaceae)
Carballo Arce, Ana Francis; Chieu Anh, Kim Ta; do Nascimento Rocha, Marco Eduardo; Rui, Liu; Harmsen, Irene; Mogg, Christopher; Otárola-Rojas, Marco; Garcia, Mario; Sánchez Vindas, Pablo; Poveda, Luis; Rajagopal Subramaniam; Smith, Myron; Coelho Kaplan, Maria Auxiliadora; Figueiredo, Maria Raquel; Durst, Tony; Arnason, John (NRC Research Press, 2015)The Marcgraviaceae is a neotropical plant family of lianas and shrubs distributed throughout Central and South America, mainly in evergreen and semi-evergreen tropical forests. In this study, extracts of 12 Marcgraviaceae ... -
Efficacy of Souroubea-Platanus Dietary Supplement Containing Triterpenes in Beagle Dogs Using a Thunderstorm Noise-Induced Model of Fear and Anxiety
Masic, Aleksandar; Landsberg, Gary; Milgram, Bill.; Merali, Zul.; Durst, Tony; Sánchez Vindas, Pablo; Garcia, Mario; Baker, John; Liu, Rui; Arnason, John (Multidisciplinary Digital Publishing Institute, 2021-04-03)A novel botanical dietary supplement, formulated as a chewable tablet containing a defined mixture of Souroubea spp. vine and Platanus spp. Bark, was tested as a canine anxiolytic for thunderstorm noise-induced stress ... -
New Botanical Anxiolytics for Use in Companion Animals and Humans
Liu, Rui; Ahmed, Fida; Cayer, Christian; Mullally, Martha; Carballo Arce, Ana Francis; Otarola Rojas, Marco; Garcia, Mario; Baker, John; Masic, Aleksandar; Sanchez, Pablo E.; Poveda, Luis; Merali, Zul; Durst, Tony; Arnason, John T. (Springer (Alemania), 2017-11)As part of our ongoing research into botanical therapies for anxiety disorders, the neotropical vine Souroubea sympetala was chosen for study as a phytochemical discovery strategy focusing on rare Central American plant ...