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Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties
(Xi'an Jiaotong University, 2019-07-10)
Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the ...