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Irbesartan desmotropes: Solid-state characterization, thermodynamic study and dissolution properties
(Xi'an Jiaotong University, 2019-07-10)
Irbesartan (IBS) is a tetrazole derivative and antihypertensive drug that has two interconvertible structures, 1H- and 2H-tautomers. The difference between them lies in the protonation of the tetrazole ring. In the ...
Drug Solubility Enhancement through the Preparation of Multicomponent Organic Materials: Eutectics of Lovastatin with Carboxylic Acids
(MDPI AG, 2019-03)
Lovastatin (LOV) is a drug used to treat hypercholesterolemia. Recent studies have
identified its antioxidant effects and potential use in the treatment of some types of cancer. However,
the low bioavailability related ...
Escrutinio optimizado de amplio espectro cualitativo y alternativo de aplicación forense por HPLC/ DAD para drogas y medicamentos
(Universidad Nacional (Costa Rica), 2011-10)
Con el desarrollo de este trabajo, se implementó un método de escrutinio de amplio espectro de drogas y medicamentos, utilizando cromatografía líquida de alta resolución (HPLC), con detector de arreglo de diodos (DAD), el ...