Now showing items 1-20 of 167

    • A novel host-adapted strain of Salmonella Typhimurium causes renal disease in olive ridley turtles (Lepidochelys olivacea) in the Pacific 

      Thierry, Work; Dagenais, Julie; Stacy, Brain; Ladner, Jason; Lorch, Jeffrey; Balazs, George; BARQUERO-CALVO, ELIAS; Breeden, Renee; Corrales Gómez, Natalia; Berlowski-Zier, Brenda; Gonzalez-Barrientos, Rocio; Harris, Heather; Hernández-Mora, Gabriela; Herrera-Ulloa, Ángel; Hesami, Shoreh; Jones, Todd; Morales, Juan Alberto; Norton, Terry M.; Rameyer, Robert A.; Taylor, Daniel; Waltzek, Thomas (Universidad Nacional, Costa Rica, 2019-06-27)
      Salmonella spp. are frequently shed by wildlife including turtles, but S. enterica subsp. enterica serovar Typhimurium or lesions associated with Salmonella are rare in turtles. Between 1996 and 2016, we necropsied 127 ...
    • Activation of Rho and Rab GTPases dissociates Brucella abortus internalization from intracellular trafficking 

      Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Méresse, Stephane; Desjardins, Michel; Pizarro-Cerdá, Javier; Badilla, Jenny; Gorvel, Jean-Pierre; Moreno, Edgardo (Blackwell Science, 2002-10-04)
      Brucella abortus is an intracellular pathogen that relies on unconventional virulence factors to infect hosts. In non-professional phagocytes, Rho GTPasesactivation by the Escherichia coli cytotoxic necrotiz ing factor ...
    • An environmental niche model to estimate the potential presence of venezuelan equine encephalitis virus in Costa Rica 

      León, Bernal; Jiménez-Sánchez, Carlos; Retamosa Izaguirre, Mónica (International Journal of Environmental Research and Public Health, 2020-12-30)
      Venezuelan equine encephalitis virus (VEEV) is an arbovirus transmitted by arthropods, widely distributed in the Americas that, depending on the subtype, can produce outbreaks or yearly cases of encephalitis in horses ...
    • Analysis of TcdB proteins within the hypervirulent clade 2 reveals an impact of RhoA glucosylation on Clostridium difficile proinflammatory activities 

      Guzman-Verri, Caterina; Quesada-Gómez, Carlos; López-Ureña, Diana; Chumbler, Nicole; Kroh, Heather; Castro-Peña, Carolina; Rodríguez, César; Orozco-Aguilar, Josué; González-Camacho, Sara; Rucavado, Alexandra; Lawley, Trevor; Lacy, D. Borden; Chaves-Olarte, Esteban (Infection and Immunity, 2016-03)
      Clostridium difficile strains within the hypervirulent clade 2 are responsible for nosocomial outbreaks worldwide. The increased pathogenic potential of these strains has been attributed to several factors but is still ...
    • Analysis of the association between density of Helicobacter spp and gastric lesions in dogs 

      Suárez-Esquivel, Marcela; Alfaro-Alarcón, Alejandro; Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS (American Journal of Veterinary Research, 2017-12)
      OBJECTIVE To evaluate the correlation between the density of native gastric Helicobacter spp and the presence of gastric lesions in dogs. ANIMALS 80 dogs of various breeds, sexes, and ages. PROCEDURES Gastroscopic and ...
    • Anatomía del sistema respiratorio y del corazón del perezoso (Choloepus hoffmanni) de Costa Rica 

      Coto Sanabria, Sofía; Vega Alfaro, Jazmín Fiorella; Cendra Villalobos, Estefanía; Chaverri Esquivel, Laura; Vigil Esquivel, Daira Jimena; Viloria Hernández, Rebeca Melissa; Pequeno, Andréia Passos (Universidad Nacional, Costa Rica, 2021-04-12)
      The two-toed sloth (Choloepus hoffmanni) faces various diseases related to the respiratory and circulatory system. Thus, prior knowledge of anatomy becomes relevant since it contributes to the study and ...
    • Apparent lack of evidence on selected infectious agents in wild Yellow-naped Amazon parrots: implications for releasing attempts 

      Dolz, Gaby; Blanco-Peña, Kinndle; Niehaus, Carmen; Salinas, Alejandro; Jiménez-Soto, Mauricio (Universidad Nacional, Costa Rica, 2015-05-09)
      Blood and feather samples, as well as oropharyngeal and cloacal swabs, were collected from nine free-ranging Amazona auropalliata between January and May 2009 in two highly modified landscapes in northern Costa Rica. ...
    • Application of multiplex quantitative Polymerase chain reaction methods to detect common bacterial fish pathogens in Nile tilapia, Oreochromis niloticus, hatcheries in Costa Rica 

      Kenelty, Kirsten; Barum, Samantha; Soto, Esteban; López-Porras, Adrián; Elizondo-Ovares, Carolina; Chaves Hernández, Aida J.; Camus, Alvin; Griffin, Matt; BARQUERO-CALVO, ELIAS (WILEY, 2018-09-29)
      Edwardsiella spp., Streptococcus spp., and Francisella noatunensis subsp. orientalis are some of the most important fish pathogens affecting global tilapia, Oreochromis spp., aquaculture. In Costa Rica, the aquaculture ...
    • Aspectos epidemiológicos de la brucelosis en humanos en las Áreas Rectoras Aguas Zarcas y Los Chiles, Costa Rica, 2015-2017 

      Rosales Galeano, Claudia; Puentes Mojica, Claudia; Arias Rojas, Oldemar; ROMERO-ZUÑIGA, JUAN JOSÉ (Universidad Nacional, Costa Rica, 2020-02-02)
      La brucelosis es una enfermedad zoonótica causada por especies del género Brucella spp., con baja notificación y subregistro en Costa Rica, especialmente en personas y en bovinos. Se determina la seroprevalencia ...
    • Bacterial counts in spleen 

      BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Moreno, Edgardo (Bio-protocol, 2013-11-05)
      Bacterial loads can be determined as colony forming units (CFU) at any point of the infection by culturing spleen homogenates on agar plates. This is a reliable method for comparing the kinetics of infection in various ...
    • Brucella abortus induces the premature death of human neutrophils through the action of Its lipopolysaccharide 

      Guzman-Verri, Caterina; BARQUERO-CALVO, ELIAS; Mora-Cartín, Ricardo; Arce-Gorvel, Vilma; de Diego, Juana L.; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Buret, Andre; Gorvel, Jean-Pierre; Moreno, Edgardo (PLoS Pathogens, 2015-05-06)
      Most bacterial infections induce the activation of polymorphonuclear neutrophils (PMNs), enhance their microbicidal function, and promote the survival of these leukocytes for protracted periods of time. Brucella abortus ...
    • Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern 

      Palacios-Chaves, Leyre; Conde-Álvarez, Raquel; Gil-Ramírez, Yolanda; Zúñiga-Ripa, Amaia; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Arce-Gorvel, Vilma; Gorvel, Jean-Pierre; Moreno, Edgardo; de Miguel, María-Jesús; Grilló, María-Jesús; Moriyon, Ignacio; Iriarte, Maite (PLoS One, 2011-01-07)
      The brucellae are a-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated ...
    • Brucella abortus senses the intracellular environment through the BvrR/Bvrs two-component system, which allows B. abortus to adapt to its replicative nich 

      Altamirano-Silva, Pamela; Meza-Torres, Jazmín; Castillo-Zeledón, Amanda; Ruiz-Villalobos, Nazareth; Zúñiga Pereira, Ana Mariel; Chacón-Díaz, Carlos; Moreno, Edgardo; Guzman-Verri, Caterina; Chaves-Olarte, Esteban (American Society for Microbiology., 2018-01-16)
      Brucella abortus is a facultative extracellular-intracellular pathogen belonging to a group of Alphaproteobacteria that establishes close interactions with animal cells. This bacterium enters host cells in a membrane-bound ...
    • Brucella abortus strain 2308 Wisconsin genome: Importance of the definition of reference strains 

      Castillo-Zeledón, Amanda; Suárez-Esquivel, Marcela; Ruiz-Villalobos, Nazareth; Jiménez-Rojas, César; Roop, R. Martin; Comerci, Diego J.; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Caswell, Clayton C.; Baker, Kate; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; LETESSON, Jean-Jacques; De Bolle, Xavier; Guzman-Verri, Caterina (Frontiers in Microbiology, 2016-09-29)
      La brucelosis es una enfermedad infecciosa bacteriana que afecta a una amplia gama de mamíferos y una zoonosis desatendida causada por especies del género genéticamente homogéneo Brucella. Como en la mayoría de los estudios ...
    • Brucella abortus uses a stealthy strategy to avoid activation of the innate immune system during the onset of infection 

      BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Weiss, David; Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Rucavado, Alexandra; Moriyon, Ignacio; Moreno, Edgardo (PLOS ONE, 2007-07-18)
      Background. To unravel the strategy by which Brucella abortus establishes chronic infections, we explored its early interaction with innate immunity. Methodology/Principal Findings. Brucella did not induce proinflammatory ...
    • Brucella canis is an intracellular pathogen that induces a lower proinflammatory response than smooth zoonotic counterparts 

      Guzman-Verri, Caterina; Chacón-Díaz, Carlos; Altamirano-Silva, Pamela; González-Espinoza, Gabriela; Medina, María-Concepción; Alfaro-Alarcón, Alejandro; Bouza-Mora, Laura; Jiménez-Rojas, César; Wong, Melissa; BARQUERO-CALVO, ELIAS; Rojas, Norman; Moreno, Edgardo; Chaves-Olarte, Esteban (Infection and Immunity, 2015-09-29)
      Canine brucellosis caused by Brucella canis is a disease of dogs and a zoonotic risk. B. canis harbors most of the virulence determinants defined for the genus, but its pathogenic strategy remains unclear since it has not ...
    • Brucella ceti and brucellosis in cetaceans 

      Guzman-Verri, Caterina; González-Barrientos, Rocio; Hernández-Mora, Gabriela; Morales, Juan Alberto; BARQUERO-CALVO, ELIAS; Chaves-Olarte, Esteban; Moreno, Edgardo (Frontiers in cellular and infection microbiology, 2012-02-06)
      Since the first case of brucellosis detected in a dolphin aborted fetus, an increasing number of Brucella ceti isolates has been reported in members of the two suborders of cetaceans: Mysticeti and Odontoceti. Serological ...
    • Brucella ceti infection in dolphins from the Western Mediterranean sea 

      Guzman-Verri, Caterina; Isidoro Ayza, Marcos; Ruiz-Villalobos, Nazareth; Pérez, Lola; Muñoz, Pilar M.; Alegre, Fernando; Barberán, Montserrat; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Gonzalez-Barrientos, Rocio; Moreno, Edgardo; Blasco, José María; Domingo, Mariano (Frontiers in cellular and infection microbiology, 2012)
      Background: Brucella ceti infections have been increasingly reported in cetaceans. Brucellosis in these animals is associated with meningoencephalitis, abortion, discospondylitis', subcutaneous abscesses, endometritis and ...
    • Brucella genetic variability in wildlife marine mammals populations relates to host preference and ocean distribution 

      Suárez-Esquivel, Marcela; Baker, Kate; Ruiz-Villalobos, Nazareth; Hernandez-Mora, Gabriela; BARQUERO-CALVO, ELIAS; González-Barrientos, Rocío; Castillo-Zeledón, Amanda; Jiménez-Rojas, César; Chacón-Díaz, Carlos; Cloeckaert, Axel; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2017-07-20)
      Intracellular bacterial pathogens probably arose when their ancestor adapted from a free-living environment to an intracellular one, leading to clonal bacteria with smaller genomes and less sources of genetic plasticity. ...