Browsing Facultad de Ciencias de la Salud by Author "Lomonte, Bruno"
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An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes
Valiente, Carmen; Sittenfeld, Ana; Lomonte, Bruno; Gutiérrez, José María; Moreno, Edgardo (Elsevier, 1992)The number and isoelectric points of phospholipase A2 isoenzymes were studied in the venoms of 12 Central American crotaline snakes of the genera Bothrops, Crotalus, Lachesis and Agkistrodon. The study was carried out by ... -
Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region
Santamarıa, Carlos; Larios, Silda; Angulo, Yamileth; Pizarro Cerda, Javier; Gorveld, Jean Pierre; Lomonte, Bruno; Moreno, Edgardo (Elsevier, 2005)A short peptide derived from the C-terminal region of Bothrops asper myotoxin II, a Lys49 phospholipase A2 (PLA2), was previously found to reproduce the bactericidal activity of its parent molecule. In this study, a panel ... -
Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom Synthetic Lys49 myotoxin II-(115−129)-peptide identifies its bactericidal region
Páramo, Leandro; Lomonte, Bruno; Pizarro Cerda, Javier; Bengoechea, José Antonio; Gorvel, Jean Pierre; Moreno, Edgardo (FEBS, 1998)Mammalian group-II phospholipases A2 (PLA2) of inflammatory fluids display bactericidal properties, which are dependent on their enzymatic activity. This study shows that myotoxins II (Lys49) and III (Asp49), two group-II ... -
Bactericidal and Antiendotoxic Properties of Short Cationic Peptides Derived from a Snake Venom Lys49 Phospholipase A2
Santamaría, Carlos; Larios, Silda; Quirós, Steve; Pizarro Cerda, Javier; Gorvel, Jean Pierre; Lomonte, Bruno; Moreno, Edgardo (American Society for Microbiology, 2005-04)The activities of short synthetic, nonhemolytic peptides derived from the C-terminal region of myotoxin 11, a catalytically inactive phospholipase A(2) homologue present in the venom of the snake Bothrops asper, have been ... -
N-formyl-perosamine surface homopolysaccharides hinder the recognition of Brucella abortus by mouse neutrophils
Mora-Cartín, Ricardo; Chacón-Díaz, Carlos; Gutiérrez-Jiménez, Cristina; Gurdián-Murillo, Stephany; Lomonte, Bruno; Chaves-Olarte, Esteban; BARQUERO-CALVO, ELIAS; Moreno, Edgardo (Universidad Nacional, Costa Rica, 2016-06)Brucella abortus is an intracellular pathogen of monocytes, macrophages, dendritic cells, and placental trophoblasts. This bacterium causes a chronic disease in bovines and in humans. In these hosts, the bacterium also ... -
Virulent Brucella nosferati infecting Desmodus rotundus has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals
Hernández-Mora, Gabriela; Chacón-Díaz, Carlos; Moreira-Soto, Andres; Barrantes-Granados, Osvaldo; Suárez-Esquivel, Marcela; Viquez-Ruiz, Eunice; BARQUERO-CALVO, ELIAS; Ruiz-Villalobos, Nazareth; Hidalgo Montealegre, Daniela; González-Barrientos, Rocío; Demeter, Elena A.; Estrella-Morales, Josimar; Zúñiga-Pereira, Ana Mariel; Quesada-Gómez, Carlos; Chaves-Olarte, Esteban; Lomonte, Bruno; Guzman-Verri, Caterina; Drexler, Jan Felix; Moreno, Edgardo (American Society for Microbiology, 2023-07-05)Desmodus rotundus, vampire bats, transmit dangerous infections, and brucellosis is a hazardous zoonotic disease, two adversities that coexist in the subtropical and tropical areas of the American continent. Here, we ...