Now showing items 21-39 of 39

    • In vivo proteolytic degradation of the Escherichia coli acyltransferase HlyC 

      Guzman-Verri, Caterina; Chaves-Olarte, Esteban; García, Fernando; Arvidson, Staffan; Moreno, Edgardo (The American Society for Biochemistry and Molecular Biology, 2001-05-18)
      Escherichia coli hemolysin (HlyA) is the prototype toxin of a major family of exoproteins produced by Gram-negative bacteria known as “repeats in toxins.” Only fatty acid-acylated HlyA molecules at residues Lys564 and ...
    • Intracellular adaptation of Brucella abortus 

      Lamontagne, Julie; Forest, Anik; Marazzo, Elena; François, Denis; Butler, Heather; Michaud, Jean-François; Boucher, Lyne; Pedro, Ida; Villeneuve, Annie; Sitnikov, Dmitri; Trudel, Sylvie; Nassif, Najib; Boudjelt, Djamila; Tomaki, Fadi; Chaves-Olarte, Esteban; Guzman-Verri, Caterina; Brunet, Sylvain; Côté-Martin, Alexandra; Hunter, Joanna; Moreno, Edgardo; Paramithiotis, Eustache (Universidad Nacional, Costa Rica, 2009-03)
      Macrophages were infected with virulent B. abortus strain 2308 or attenuated strain 19. Intracellular bacteria were recovered at different times after infection and their proteomes compared. The virulent strain initially ...
    • Isolation and identification of Arcobacter species from Costa Rican poultry production and retail sources 

      Zumbado, Leana; Barboza, Karol; Angulo, Irina; Redondo-Solano, Mauricio; Castro, Eduardo; Arias, María Laura (Journal of food protection, 2017-04-03)
      Arcobacter is a gram-negative rod recognized as a potential food- and waterborne pathogen; nevertheless, little is known about the effects of this pathogen on human and animal health. Although Arcobacter species are commonly ...
    • Legionella and the Prevention of Legionellosis Fuente física versus electrónica en la toma de decisiones del traductor 

      Chaves Araya, Anabelle (Escuela de Literatura y Ciencias del Lenguaje, 2010)
    • Microbial gene exchange on microplastic particles 

      Arias Andrés, Maria de Jesús (University of Potsdam. Faculty of Science. Institute for Biochemistry and Biology (IBB), 2018)
    • Muestreo de las Floraciones Algales Nocivas (FANs) en el Golfo de Nicoya, Puntarenas, Costa Rica 

      Calvo Vargas, Emilia; Arguedas Rodríguez, María del Pilar (2013-08-22)
      Las floraciones algales, conocidas como mareas rojas son cambios en la coloración del agua producidas por la proliferación de microorganismos pigmentados (Reguera 2002). Estos organismos presentan ciclos de crecimiento y ...
    • Neutrophils as Trojan Horse vehicles for Brucella abortus macrophage infection 

      Gutiérrez-Jiménez, Cristina; Mora-Cartín, Ricardo; Altamirano-Silva, Pamela; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Moreno, Edgardo; BARQUERO-CALVO, ELIAS (Universidad Nacional, Costa Rica, 2019-05-07)
      Brucella abortus is a stealthy intracellular bacterial pathogen of animals and humans. This bacterium promotes the premature cell death of neutrophils (PMN) and resists the killing action of these leukocytes. B. abortus-infected ...
    • Neutrophils dampen adaptive immunity in Brucellosis 

      Mora-Cartín, Ricardo; Gutiérrez-Jiménez, Cristina; Alfaro-Alarcón, Alejandro; Chaves-Olarte, Esteban; Chacón-Díaz, Carlos; BARQUERO-CALVO, ELIAS; Moreno, Edgardo (American Society For Microbiology, 2019-04-23)
      Brucella organisms are intracellular stealth pathogens of animals and humans. The bacteria overcome the assault of innate immunity at early stages of an infection. Removal of polymorphonuclear neutrophils (PMNs) at the ...
    • Neutrophils exert a suppressive effect on Th1 responses to intracellular pathogen Brucella abortus 

      BARQUERO-CALVO, ELIAS; Martirosyan, Anna; Ordoñez-Rueda, Diana; Arce-Gorvel, Vilma; Alfaro-Alarcón, Alejandro; Lepidi, Hubert; Malissen, Bernard; Malissen, Marie; Gorvel, Jean-Pierre; Moreno, Edgardo (PLoS Pathogens, 2013-02-14)
      Polymorphonuclear neutrophils (PMNs) are the first line of defense against microbial pathogens. In addition to their role in innate immunity, PMNs may also regulate events related to adaptive immunity. To investigate the ...
    • Novel genotype of Ehrlichia canis detected in samples of human blood bank donors in Costa Rica 

      Dolz, Gaby; Bouza-Mora, Laura; Solórzano-Morales, Antony; Romero-Zúñiga, Juan José; Salazar Sanchez, Lizbeth; Labruna, Marcelo Bahia; Aguiar, Daniel M. (Ticks and Tick- borne Diseases, 2017-09-23)
      This study focuses on the detection and identification of DNA and antibodies to Ehrlichia spp. in samples of blood bank donors in Costa Rica using molecular and serological techniques. Presence of Ehrlichia canis was ...
    • Optimización de la técnica de PCR Punto Final y Tiempo Real para la detección de Salmonella enterica subsp. enterica serotipo Gallinarum en aislamientos bacterianos y tejidos biológicos obtenidos a partir de aves de corral 

      Leza Leza, Makayla Tatiana (Universidad Nacional, Costa Rica, 2020)
      Las especies del género Salmonella son importantes patógenos zoonóticos que ocasionan grandes pérdidas económicas y problemas sanitarios en todo el mundo. Dentro de estas se encuentra Salmonella enterica subsp. enterica ...
    • Persistence of Brucella abortus in the bone marrow of infected mice 

      Gutiérrez-Jiménez, Cristina; HYSENAJ, LISIENA; Alfaro-Alarcón, Alejandro; Mora-Cartín, Ricardo; Gorvel, Jean-Pierre; Arce-Gorvel, Vilma; Moreno, Edgardo; BARQUERO-CALVO, ELIAS (Journal of Immunology Research, 2018-12-03)
      Brucellosis is a zoonotic bacterial infection that may persist for long periods causing relapses in antibiotic-treated patients. The ability of Brucella to develop chronic infections is linked to their capacity to invade ...
    • Persistence of Brucella abortus lineages revealed by genomic characterization and phylodynamic analysis 

      Suárez-Esquivel, Marcela; Henández-Mora, Gabriela; Ruiz-Villalobos, Nazareth; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; LadnerI, JasonT.; Oviedo-Sánchez, Gerardo; Foster, JeffreyT.; Rojas-Campos, Norman; Chaves-Olarte, Esteban; Thomson, Nicholas; Moreno, Edgardo; Guzman-Verri, Caterina (Universidad Nacional, Costa Rica, 2020-04-14)
      Brucellosis, caused by Brucella abortus, is a major disease of cattle and humans worldwide distributed. Eradication and control of the disease has been difficult in Central and South America, Central Asia, the Mediterranean ...
    • Purification of intracellular bacteria: isolation of viable Brucella abortus from host cells 

      Chaves-Olarte, Esteban; Altamirano-Silva, Pamela; Guzman-Verri, Caterina; Moreno, Edgardo (Springer Science, Business Media Nueva York, 2014, 2014)
      The pathogenesis of brucellosis depends on the ability of bacteria from the genus Brucella to invade and replicate within animal cells. To understand the molecular pathways used by Brucella spp. to reach its intracellular ...
    • Reporte de caso clínico Primer diagnóstico de Rhodococcus equi confirmado, laboratorialmente, en un potrillo de Costa Rica 

      Estrada McDermott, Pedro; Murillo Ramírez, Carla; Razquin, Patricio; BARQUERO-CALVO, ELIAS; Chacón-Díaz, Carlos; Estrada, Juan Manuel (Universidad Nacional, Costa Rica, 2020-03-09)
      Neumonía por Rhodococcus equi es importante causa de morbilidad y mortalidad en potrillos de todo el mundo. La prevalencia y/o virulencia de la bacteria es, aparentemente, baja en Costa Rica, pues nunca han sido reportados ...
    • The differential interaction of brucella and ochrobactrum with innate immunity reveals traits related to the evolution of stealthy pathogens 

      BARQUERO-CALVO, ELIAS; Conde-Álvarez, Raquel; Chacón-Díaz, Carlos; Quesada-Lobo, LucÍa; Martirosyan, Anna; Guzman-Verri, Caterina; Iriarte, Maite; Manček Keber, Mateja; Jerala, Roman; Gorvel, Jean-Pierre; Moriyon, Ignacio; Moreno, Edgardo; Chaves-Olarte, Esteban (PLOS ONE, 2009-06-16)
      Background: During evolution, innate immunity has been tuned to recognize pathogen-associated molecular patterns. However, some a-Proteobacteria are stealthy intracellular pathogens not readily detected by this system. ...
    • The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition 

      Moreno, Edgardo; BARQUERO-CALVO, ELIAS; Conde-Álvarez, Raquel; Arce-Gorvel, Vilma; Iriarte, Maite; Manček Keber, Mateja; Palacios-Chaves, Leyre; Chacón-Díaz, Carlos; Chaves-Olarte, Esteban; Martirosyan, Anna; von Bargen, Kristine; Grilló, María-Jesús; Jerala, Roman; Brandenburg, Klaus ; Llobet, Enrique; Bengoechea, José A.; Moriyon, Ignacio; Gorvel, Jean-Pierre (PLoS Pathogens, 2012-05-10)
      Innate immunity recognizes bacterial molecules bearing pathogen-associated molecular patterns to launch inflammatory responses leading to the activation of adaptive immunity. However, the lipopolysaccharide (LPS) of the ...
    • Veterinarios explican cómo la Brucella resiste acción del sistema inmune 

      Núñez Z., Johnny (Oficina de Comunicación, Universidad Nacional, 2019-02)
      Estudio de la Escuela de Medicina Veterinaria evidenció que dicha bacteria resiste y se replica en las células encargadas de contrarrestar las infecciones bacterianas en el organismo
    • What have we learned from brucellosis in the mouse model? 

      Moreno, Edgardo; Grilló, María-Jesús; Blasco, José María; Gorvel, Jean-Pierre; Moriyon, Ignacio (Veterinary Research, 2012)
      Brucellosis is a zoonosis caused by Brucella species. Brucellosis research in natural hosts is often precluded by practical, economical and ethical reasons and mice are widely used. However, mice are not natural Brucella ...